162934-73-8 Usage
Description
Naphthalen-1-yl(1-pentyl-1H-pyrrol-3-yl)methanone, also known as JWH-030, is a synthetic cannabinoid agonist that selectively binds to the CB1 receptor. It is characterized by its naphthalene and pyrrole moieties connected through a pentyl chain, which contributes to its unique chemical properties and biological activity.
Uses
Used in Pharmaceutical Research:
Naphthalen-1-yl(1-pentyl-1H-pyrrol-3-yl)methanone is used as a synthetic pyrrole agonist for the study of cannabinoid receptors. Its interaction with the CB1 receptor allows researchers to investigate the effects of synthetic cannabinoids on various physiological processes and potential therapeutic applications.
Used in Drug Development:
In the pharmaceutical industry, naphthalen-1-yl(1-pentyl-1H-pyrrol-3-yl)methanone serves as a lead compound for the development of novel drugs targeting the endocannabinoid system. Its ability to modulate CB1 receptor activity can be leveraged to create medications for the treatment of various disorders, such as pain, inflammation, and neurological conditions.
Used in Toxicological Studies:
Due to its agonistic effects on the CB1 receptor, naphthalen-1-yl(1-pentyl-1H-pyrrol-3-yl)methanone is also utilized in toxicological research to understand the potential risks and side effects associated with synthetic cannabinoid use. This knowledge is crucial for the safe development and application of cannabinoid-based therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 162934-73-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,9,3 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 162934-73:
(8*1)+(7*6)+(6*2)+(5*9)+(4*3)+(3*4)+(2*7)+(1*3)=148
148 % 10 = 8
So 162934-73-8 is a valid CAS Registry Number.
162934-73-8Relevant articles and documents
Direct synthesis of: N -aryl/alkyl 3-carbonylpyrroles from the Morita-Baylis-Hillman acetate of 2,2-dimethoxyacetaldehyde and a primary amine
Gu, Yanlong,Guo, Luxia,Li, Jiaqi,Li, Minghao,Vaccaro, Luigi
supporting information, p. 9465 - 9469 (2021/12/09)
N-Aryl/alkyl 3-carbonylpyrroles are ubiquitous in compounds of biological and material significance, whereas their synthesis traditionally requires a multistep protocol. Herein a kalinite catalyzed direct synthesis of N-substituted 3-carbonylpyrroles from a 2,2-dimethoxyacetaldehyde derived Morita-Baylis-Hillman acetate and a primary amine in ethanol is developed. This reaction is scalable and also applicable to the synthesis of JMH-030, JMC-2004 and other bioactive compounds. This journal is
