16319-93-0

Basic information

• Product Name: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate
• Synonyms: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate;17-Acetyloxy-3-ethoxypregna-3,5-dien-20-one;3-Ethoxypregna-3,5-dien-17-ol-20-one-17-acetate;17α-Acetoxy-3-ethoxypregna-3,5-dien-20-one
• CAS NO: 16319-93-0
• Molecular Formula: C₂₅H₃₆O₄
• Molecular Weight: 400.55094
• EINECS: 240-396-4
• Product Categories: Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 16319-93-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 515.9°Cat760mmHg
• Flash Point: 220.8°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(16319-93-0)
• EPA Substance Registry System: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(16319-93-0)

Safety Data

• Hazardous Substances Data: 16319-93-0(Hazardous Substances Data)

Usage

Description

3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is a chemical compound derived from the pregnane class of steroid hormones. It is characterized by its unique molecular structure, featuring a 3-ethoxy group and a 17-acetate group, along with a 3,5-dien system. 3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is known for its yellow crystalline appearance and is primarily used as an intermediate in the synthesis of other steroidal compounds, such as Progesterone.

Uses

Used in Pharmaceutical Industry:
3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is used as an intermediate in the preparation of Progesterone (P755900) impurity for the pharmaceutical industry. Its role in the synthesis process is crucial, as it helps in the development of medications that target various health conditions related to hormonal imbalances and reproductive health.
Chemical Properties:
The compound is characterized by its yellow crystalline appearance, which is a common feature among steroidal compounds. This property is indicative of its stability and purity, making it suitable for use in the pharmaceutical industry as a starting material for further chemical reactions and synthesis.

InChI:InChI=1/C25H36O4/c1-6-28-19-9-12-23(4)18(15-19)7-8-20-21(23)10-13-24(5)22(20)11-14-25(24,16(2)26)29-17(3)27/h7,15,20-22H,6,8-14H2,1-5H3/t20-,21+,22+,23+,24+,25+/m1/s1

Upstream product

• 4134-58-1 hydroxyprogesterone acetate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 1178-60-5 gestovis 
• 2477-73-8 17α-acetoxy-6α-chloropregn-4-ene-3,20-dione 
• 302-22-7 chlormadinone acetate 
• 151-69-9 17-acetoxy-6α-chloro-pregna-1,4-diene-3,20-dione 

Relevant articles and documents

METHOD FOR PREPARING MEDROGESTONE

A method for the preparation of medrogestone by heterogeneously palladium- catalysed isomerisation from 17-methyl-6-methylenepregn-4-ene-3,20-dione is described.