1633-82-5 Usage
Description
3-Chloropropanesulfonyl chloride is a chemical compound that serves as an intermediate in the synthesis of various pharmaceutical intermediates. It is a clear colorless to light brown liquid and is known for its reactivity in chemical reactions.
Uses
Used in Pharmaceutical Industry:
3-Chloropropanesulfonyl chloride is used as an intermediate for the preparation of many enzymatic inhibitors. Its application in this industry is due to its ability to facilitate the synthesis of compounds that can inhibit the activity of certain enzymes, which can be beneficial in the development of drugs targeting specific enzyme-related diseases.
Used in Organic Chemistry:
3-Chloropropanesulfonyl chloride is used as a reagent in the generation and trapping of derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids. This process provides chiral sultams and sultones, which are valuable in the field of organic chemistry for their unique properties and potential applications in various chemical reactions and syntheses.
Overall, 3-Chloropropanesulfonyl chloride is a versatile compound with applications in both the pharmaceutical and organic chemistry industries, primarily due to its role as an intermediate in the synthesis of enzymatic inhibitors and its utility in generating chiral sultams and sultones.
Check Digit Verification of cas no
The CAS Registry Mumber 1633-82-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,3 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1633-82:
(6*1)+(5*6)+(4*3)+(3*3)+(2*8)+(1*2)=75
75 % 10 = 5
So 1633-82-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H6Cl2O2S/c4-2-1-3-8(5,6)7/h1-3H2
1633-82-5Relevant articles and documents
Combined 17O NMR Spectra and 18O Isotope Effects in 13C NMR Spectra for Oxygen Labeling Studies. Carbon->Sulfur Oxygen Migration in the Aqueous Chlorination of Mercapto Alcohols
King, J. F.,Skonieczny, S.,Khemani, K.C.,Stothers, J.B.
, p. 6514 - 6515 (1983)
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Structural Engineering and Optimization of Zwitterionic Salts for Expeditious Discovery of Thermoresponsive Materials
Chen, Chien-Yuan,Chen, Jin-Syuan,Chu, Yen-Ho
supporting information, (2022/01/06)
This work reported the discovery of N-triflimide (NTf)-based zwitter-ionic liquids (ZILs) that exhibit UCST-type phase transitions in water, and their further structural optimization in finetuning polarity to ultimately afford newfangled thermosensitive materials carrying attractive and biocompatible Tc values that clearly demonstrated the true value of the tunability of ZIL structure. This research established that with non-aromatic, acyclic ZILs as small-molecule thermoresponsive materials, their mixing and de-mixing with water triggered by temperatures are entirely reversible.
Bispiperidines as antithrombotic agents
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, (2008/06/13)
Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents
