163808-09-1

Basic information

• Product Name: 4-AMINOBENZOOXAZOL
• Synonyms: 4-AMINOBENZOOXAZOL ;Benzooxazol-4-ylamine;4-BenzoxazolaMine;Benzo[d]oxazol-4-aMine;1,3-Benzoxazol-4-amine, 4-Aminobenzo[d]oxazole;4-Aminobenzooxazole;4-Aminobenzoxazole
• CAS NO: 163808-09-1
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.13534
• Mol File: 163808-09-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 77-79°
• Boiling Point: 282.296 °C at 760 mmHg
• Flash Point: 124.528 °C
• Appearance: /
• Density: 1.317 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.16±0.30(Predicted)
• CAS DataBase Reference: 4-AMINOBENZOOXAZOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINOBENZOOXAZOL(163808-09-1)
• EPA Substance Registry System: 4-AMINOBENZOOXAZOL(163808-09-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 163808-09-1(Hazardous Substances Data)

Usage

General Description

4-Aminobenzooxazol, also known as 4-ABO, is a chemical compound with the molecular formula C7H6N2O. It is a benzooxazole derivative and is commonly used in the synthesis of pharmaceuticals and dyestuffs. 4-ABO has a wide range of applications in the fields of medicine, agriculture, and materials science, specifically in the production of fluorescent dyes and pigments. It is also used as a reagent and intermediate in organic synthesis, particularly in the creation of heterocyclic compounds. Additionally, 4-ABO has been studied for its potential pharmacological properties, including its anticonvulsant and neuroprotective effects. However, it is important to handle this chemical with caution as it may be hazardous if not properly managed.

Upstream product

• 163808-13-7 4-nitrobenzo[d]oxazole 
• 603-85-0 2-Amino-3-nitrophenol 

Downstream Products

• 163808-08-0 4-hydroxy-1-methyl-1H-benzimidazole 
• 1380314-32-8 C₁₇H₁₈N₂O₃S 
• 1380314-29-3 C₁₄H₉F₃N₂O₃S 
• 1380314-28-2 C₁₄H₁₂N₂O₃S 
• 478553-46-7 C₁₄H₁₂N₂O₄S 
• 1380314-65-7 3-tosyl-7-hydroxybenzimidazole 
• 1223569-58-1 (E)-N-benzoxazol-4-yl-3-(3-acetoxy-4-methoxyphenyl)prop-2-enamide 
• 959246-43-6 tert-butyl benzo[d]oxazole-4-ylcarbamate 

Relevant articles and documents

COMPOUND HAVING ZNF143 INHIBITORY ACTIVITY AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having a ZNF143 inhibitory activity as well as to provide a ZNF143 inhibitory agent and pharmaceutical composition containing the same. SOLUTION: Provided is a compound represented by formula (I) or a salt thereof as well as a ZNF143 inhibitory agent containing the same and a pharmaceutical composition having the same as an active ingredient. A-B-C-D (I)[A is H, a methyl group, a naphthyl group, a phenyl group or a nitrogen-containing heterocyclic ring; B is as shown below, and C is an amide bond or a heteroaromatic ring containing N and O; D is a substituted/unsubstituted phenyl group or a monocyclic heteroaromatic ring containing N or S; and C and D are both fused heterocyclic ring or the like optionally having a substituent group.]. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 4H-chromenes and analogs thereof, represented by the Formula (I): wherein R1, R3-R5, A, D, Y and Z are defined herein. The present invention also relates to the discovery that compounds having Formula (I) are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.