163959-79-3Relevant articles and documents
PF74 and its novel derivatives stabilize hexameric lattice of HIV-1 mature-like particles
?kach, Kry?tof,Dostálková, Al?běta,Flegel, Martin,Hadravová, Romana,Hrabal, Richard,K?í?ová, Ivana,Kaufman, Filip,Ruml, Tomá?,Rumlová, Michaela
, (2020/04/27)
A major structural retroviral protein, capsid protein (CA), is able to oligomerize into two different hexameric lattices, which makes this protein a key component for both the early and late stages of HIV-1 replication. During the late stage, the CA prote
Asymmetric Hydrogenation of 3,5-Bistrifluoromethyl Acetophenone in Pilot Scale with Industrially Viable Ru/Diphosphine-Benzimidazole Complexes
Xu, Liang,Huang, Zhi-Hong,Sandoval, Christian A.,Gu, Lian-Quan,Huang, Zhi-Shu
, p. 1137 - 1141 (2015/04/22)
A novel efficient asymmetric hydrogenation (AH) process was developed for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethanol (3), using a catalyst Ru/(4R,5R)-(+)-4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxoane-(R,R-Diop)-2R-(α-met
Hybrid NH2-benzimidazole ligands for efficient Ru-catalyzed asymmetric hydrogenation of aryl ketones
Li, Yuehui,Ding, Kuiling,Sandoval, Christian A.
supporting information; experimental part, p. 907 - 910 (2009/07/25)
Readily available hybrid NH2/benzimidazole ligands (R-bimaH, 1) dramatically influence the outcome of established Ru-based catalysts during asymmetric hydrogenation of aryl ketones. The benzimidazole functionality results in reversal of the typically observed chiral induction and allows for hydrogenation to be uncharacteristically conducted in nonprotic solvents. The developed systems efficiently catalyzed the AH of a number of ketones in up to 99% ee.