164171-61-3

Basic information

• Product Name: 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile
• Synonyms: 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile
• CAS NO: 164171-61-3
• Molecular Weight: 175.187
• Mol File: 164171-61-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile(164171-61-3)
• EPA Substance Registry System: 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile(164171-61-3)

Safety Data

• Hazardous Substances Data: 164171-61-3(Hazardous Substances Data)

Upstream product

• 104516-57-6 5-(2-hydroxy-5-methylphenyl)isoxazole 
• 917373-45-6 6-methyl-4-oxo-2-(trifluoromethyl)-4H-chromene-3-carbonitrile 
• 1112890-49-9 p-tolyl-2-cyanoacetate 

Downstream Products

• 1112890-34-2 6-amino-2,10-dimethyl-7-(2-ethoxyphenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-21-7 6-amino-2,10-dimethyl-7-(4-methylphenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-23-9 6-amino-2,10-dimethyl-7-(4-fluorophenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-31-9 6-amino-2,10-dimethyl-7-(2-chlorophenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-42-2 6-amino-2,10-dimethyl-7-[(3-methyloxy-4-ethyloxy)phenyl]-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-20-6 6-amino-2,10-dimethyl-7-(4-methoxyphenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-45-5 6-amino-2,10-dimethyl-7-(2,4-dichlorophenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 
• 1112890-36-4 6-amino-2,10-dimethyl-7-(4-N,N-dimethylaminophenyl)-7H-5,13-dioxa-14-aza-benzo[a]naphthacen-8-one 

Relevant articles and documents

Base-catalyzed and solvent-dependent cascade reaction in the regioselective synthesis of novel fused polycycles

A novel base-catalyzed cascade reaction induced by Knoevenegal condensation that can regioselectively generate cyanoflavanones and heavily fused polycycles with intensive fluorescence and high quantum yields is reported. The reaction is solvent-dependent, low-polarity solvents promote the formation of polycycles while high-polarity solvents favor the conversion to cyanoflavanones. A possible mechanism for such serial transformations is proposed.

Benzo-γ-pyrones. Part XV. Conversion of some 4-Oxo-4H-1-benzopyran-2-carboxylic Acids into 4H-1-Benzopyran-4-ones via Isoxazoles

The preparation of 5-substituted-3-isoxazolecarboxylic acids 2a-c and their transformation into the corresponding 2-aminochromones (5a-c) and 3-cyano-2-methylchromones (6a-c) is described. The structures of oximes of methylchromones were revised to isoxazoles 2d-f. The structures of the obtained compounds were proved by spectral methods (1H, 13C NMR, IR and MS). Key words: chromones, isoxazoles, NMR and MS spectra