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16563-93-2

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16563-93-2 Usage

General Description

3-hydroxy-3-hydroxymethyloxetane, also known as 3-HO, is a chemical compound that belongs to the class of oxetanes. It is a stable and highly reactive compound that is used in a variety of applications, including as a monomer for polymer synthesis and as a building block for the production of pharmaceuticals. 3-HO is also utilized in the development of adhesives, coatings, and surfactants due to its unique chemical and physical properties. Additionally, it is being researched for its potential use in the synthesis of bio-based materials, making it a promising and versatile compound with a wide range of industrial and scientific applications.

Check Digit Verification of cas no

The CAS Registry Mumber 16563-93-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,6 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16563-93:
(7*1)+(6*6)+(5*5)+(4*6)+(3*3)+(2*9)+(1*3)=122
122 % 10 = 2
So 16563-93-2 is a valid CAS Registry Number.
InChI:InChI=1S/C4H8O3/c5-1-4(6)2-7-3-4/h5-6H,1-3H2

16563-93-2Upstream product

16563-93-2Downstream Products

16563-93-2Relevant articles and documents

Synthesis and Antiobesity Properties of 6-(4-Chlorophenyl)-3-(4-((3,3-difluoro-1-hydroxycyclobutyl)methoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one (BMS-814580): A Highly Efficacious Melanin Concentrating Hormone Receptor 1 (MCHR1) Inhibitor

Ahmad, Saleem,Washburn, William N.,Hernandez, Andres S.,Bisaha, Sharon,Ngu, Khehyong,Wang, Wei,Pelleymounter, Mary Ann,Longhi, Daniel,Flynn, Neil,Azzara, Anthony V.,Rohrbach, Kenneth,Devenny, James,Rooney, Suzanne,Thomas, Michael,Glick, Susan,Godonis, Helen,Harvey, Susan,Zhang, Hongwei,Gemzik, Brian,Janovitz, Evan B.,Huang, Christine,Zhang, Lisa,Robl, Jeffrey A.,Murphy, Brian J.

, p. 8848 - 8858 (2016/10/22)

The potent MCHR1 in vitro and in vivo antagonist activity of a series of cyclic tertiary alcohols derived from compound 2b is described. Subsequent pharmacokinetic and pharmacodynamic studies identified BMS-814580 (compound 10) as a highly efficacious antiobesity agent with a relatively clean in vitro and in vivo safety profile.

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