165807-06-7

Basic information

• Product Name: 4-Pyrimidinecarboxaldehyde, 2-amino- (9CI)
• Synonyms: 4-Pyrimidinecarboxaldehyde, 2-amino- (9CI);2-Amino-4-pyrimidinecarboxaldehyde;2-aMinopyriMidine-4-carbaldehyde
• CAS NO: 165807-06-7
• Molecular Formula: C₅H₅N₃O
• Molecular Weight: 123.1127
• Product Categories: PYRIMIDINE;pharmacetical
• Mol File: 165807-06-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 372.7 °C at 760 mmHg
• Flash Point: 179.2 °C
• Appearance: /
• Density: 1.37 g/cm³
• Vapor Pressure: 9.47E-06mmHg at 25°C
• Refractive Index: 1.666
• PKA: 2.03±0.10(Predicted)
• CAS DataBase Reference: 4-Pyrimidinecarboxaldehyde, 2-amino- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyrimidinecarboxaldehyde, 2-amino- (9CI)(165807-06-7)
• EPA Substance Registry System: 4-Pyrimidinecarboxaldehyde, 2-amino- (9CI)(165807-06-7)

Safety Data

• Hazardous Substances Data: 165807-06-7(Hazardous Substances Data)

Usage

General Description

"4-Pyrimidinecarboxaldehyde, 2-amino- (9CI)" is a chemical compound also known by its CAS Registry Number, 69849-43-6. It belongs to the class of organic compounds known as pyrimidines and pyrimidine derivatives, which are aromatic heterocyclic compounds that contain a pyrimidine ring, a six-membered ring with two nitrogen atoms and four carbon atoms. The exact structure, properties, and potential applications of this compound are not readily available in literature, implying that it may be a less-known or less-studied compound. However, given its classification, it can be extrapolated that this compound may potentially be used in the pharmaceutical industry, agricultural industry, or in scientific research.

InChI:InChI=1/C5H5N3O/c6-5-7-2-1-4(3-9)8-5/h1-3H,(H2,6,7,8)

Upstream product

• 165807-05-6 4-(dimethoxymethyl)pyrimidin-2-amine 
• 67751-23-9 (E)-4-(dimethylamino)-1,1-dimethoxybut-3-en-2-one 

Downstream Products

• 165806-48-4 5-(2-Aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1-[3-(4-Morpholinyl)propyl]imidazole 
• 165807-05-6 4-(dimethoxymethyl)pyrimidin-2-amine 

Relevant articles and documents

NEW THIENOPYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description.

8-HETEROARYLPURINE MNK2 INHIBITORS FOR TREATING METABOLIC DISORDERS

This invention relates to 8-Heteroarylpurine Mnk2 Inhibitors which are useful for the treatment and prevention of metabolic disorders such as obesity and diabetes.

Pyrimidinylimidazole inhibitors of CSBP/P38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes

Pyrimidine analogs of the pyridinylimidazole class of CSBP/p38 kinase inhibitors were prepared in an effort to reduce the potent inhibition of hepatic cytochrome P450 observed for the pyridinyl compounds. The substitution of pyrimidin-4-yl, 2-methoxypyrimidin-4-yl, or 2- methylaminopyrimidin-4-yl for pyridin-4-yl effectively dissociates CSBP/p38 kinase from P450 inhibition for this series and furthermore achieves an increase in oral activity.