16732-80-2

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester
• Synonyms: 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester;Ethyl 4-Methyl-1H-indole-2-carboxylate;4-methyl-1H-indole-2-carboxylic acid ethyl ester;4-Methylindole-2-carboxylic acid ethyl ester, 98%
• CAS NO: 16732-80-2
• Molecular Formula: C₁₂H₁₃NO₂
• Molecular Weight: 203.23712
• Mol File: 16732-80-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester(16732-80-2)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester(16732-80-2)

Safety Data

• Hazardous Substances Data: 16732-80-2(Hazardous Substances Data)

Usage

General Description

1H-Indole-2-carboxylic acid, 4-methyl-, ethyl ester is a chemical compound with the molecular formula C13H13NO2. It is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. 1H-Indole-2-carboxylic acid, 4-methyl-, ethyl ester is an ethyl ester derivative of 4-methyl-1H-indole-2-carboxylic acid, and it is often used as a starting material for the production of various drugs, such as anti-inflammatory and anti-cancer medications. It is a pale yellow liquid with a fruity odor, and it is primarily used in laboratory research and pharmaceutical manufacturing. The chemical structure of 1H-Indole-2-carboxylic acid, 4-methyl-, ethyl ester makes it a versatile and important compound in the pharmaceutical industry.

Upstream product

• 18474-57-2 4-methyl-1H-indole-2-carboxylic acid 
• 64-17-5 ethanol 
• 24512-97-8 azide 
• 81803-45-4 ethyl 2-azido-3-(2-methylphenyl)propenoate 
• 4966-38-5 (E)-ethyl pyruvate 2-(2-methylphenyl)hydrazone 
• 529-20-4 2-methylphenyl aldehyde 
• 83-41-0 2,3-dimethylnitrobenzene 
• 70467-01-5 (2-methyl-6-nitro-phenyl)-pyruvic acid 
• 796069-22-2 4-methylindole-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 

Downstream Products

• 58518-51-7 4-monomethylindolecarboxaldehyde 
• 50536-58-8 5-bromo-4-methyl-1H-indole-2-carboxylic acid 
• 229953-80-4 1-(3-cyano-benzyl)-4-methyl-1H-indole-2-carboxylic acid (4-dimethylamino)-benzyl amide 
• 18474-57-2 4-methyl-1H-indole-2-carboxylic acid 
• 229951-10-4 1-(3-carbamimidoyl-benzyl)-4-methyl-1H-indole-2-carboxylic acid 3-carbamimidoyl-benzylamide 

Relevant articles and documents

Regioselective Functionalization of 4-Methyl-1H-indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1H-indole

We report a five-step synthesis of 2-cyano-5-formyl-4-methyl-1H-indole through sequential functionalization of readily available 4-methyl-1H-indole. Cyano and aldehyde functionalities are regioselectively installed at the 2 and 5 position, respectively. T

ZrCl4-promoted facile synthesis of indole derivatives

Zirconium(iv) chloride effectively activates nitrogen (N2) extrusion from aryl azidoacrylates followed by annulation to provide the desired indole products in moderate to good yields. The reaction proceeds at low temperature and in short reaction time and is applicable to a variety of substrates.

Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents

The invention relates to heterocyclyl-substituted dihydroquinazolines of formula (I), to processes for their preparation, to medicaments containing them, and to methods for the treatment and/or prophylaxis of diseases, in particular, for use as anti-viral agents, in particular, against cytomegaloviruses.