16735-19-6

Basic information

• Product Name: dl-Cathinone Hydrochloride
• Synonyms: dl-Cathinone Hydrochloride;1-Propanone, 2-amino-1-phenyl-, hydrochloride;2-amino-1-phenyl-propan-1-one hydrochloride;2-amino-1-phenylpropan-1-one hydrochloride;Propiophenone, 2-amino-, hydrochloride;DL-Cathinone (hydrochloride) (exempt preparation);HPZCAKYHISJOIK-UHFFFAOYSA-N
• CAS NO: 16735-19-6
• Molecular Formula: C₉H₁₁NO*ClH
• Molecular Weight: 185.65068
• Mol File: 16735-19-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 185-189 °C
• Boiling Point: 255°Cat760mmHg
• Flash Point: 108°C
• Appearance: /
• Density: 1.054g/cm³
• Vapor Pressure: 0.0167mmHg at 25°C
• CAS DataBase Reference: dl-Cathinone Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: dl-Cathinone Hydrochloride(16735-19-6)
• EPA Substance Registry System: dl-Cathinone Hydrochloride(16735-19-6)

Safety Data

• Hazardous Substances Data: 16735-19-6(Hazardous Substances Data)

Usage

Description

DL-Cathinone Hydrochloride, a racemic mixture of (-)-(S)-cathinone and its less potent (+)-isomer, is a potent central stimulant and a naturally occurring analog of amphetamine. It is derived from the khat plant (C. edulis) and is chemically similar to ephedrine and amphetamines. DL-Cathinone Hydrochloride is known to exhibit antidepressant properties and is a potent releaser of norepinephrine and dopamine.

Uses

Used in Research Applications:
DL-Cathinone Hydrochloride is used as a research chemical for studying its psychoactive properties, central stimulant effects, and its potential as an antidepressant agent. It is particularly useful in understanding the mechanisms of action of amphetamine-like substances and their impact on neurotransmitter release.
Used in Forensic Applications:
DL-Cathinone Hydrochloride is used as a forensic tool for the identification and analysis of this substance in cases related to drug abuse or criminal investigations. Its analysis helps in determining the presence of khat plant derivatives in biological samples and contributes to the understanding of the substance's prevalence and distribution in society.
Used in Pharmaceutical Development:
DL-Cathinone Hydrochloride serves as a starting point for the development of new pharmaceuticals targeting central nervous system disorders. Its potent release of norepinephrine and dopamine makes it a promising candidate for the treatment of conditions such as depression, attention deficit hyperactivity disorder (ADHD), and other related disorders.
Used in Drug Abuse Prevention and Education:
DL-Cathinone Hydrochloride is used in the development of educational materials and prevention strategies aimed at raising awareness about the risks and consequences of khat plant abuse. Understanding the properties and effects of this substance can help in the creation of targeted interventions and policies to reduce its misuse and potential harm to individuals and communities.

InChI:InChI=1/C9H11NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7H,10H2,1H3;1H

Upstream product

• 56894-44-1 N-(1-methyl-2-oxo-2-phenyl-ethyl)-phthalamic acid 
• 138371-45-6 2-N-(tert-butoxycarbonyl)amino-1-phenyl-1-propanone 
• 16735-29-8 N-(1-oxo-1-phenylpropan-2-yl)benzamide 
• 16735-28-7 N-(1-methyl-2-oxo-2-phenylethyl)acetamide 
• 16735-27-6 2,2,2-trifluoro-N-(1-oxo-1-phenylpropaN-2-yl)acetamide 
• 119-51-7 1-phenyl-1,2-propanedione 2-oxime 
• 93-55-0 1-phenyl-propan-1-one 
• 100-58-3 phenylmagnesium bromide 
• 18197-26-7 sodium diformamide 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 141264-20-2 N-<2-(1-phenyl-1-oxo)ethyl>-N-formylformamide 
• 19437-20-8 2-(1-oxo-1-phenylpropan-2-yl) isoindoline-1,3-dione 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 794528-84-0 dichloro-acetic acid-(1-methyl-2-oxo-2-phenyl-ethylamide) 
• 109089-32-9 3-methyl-2-phenyl-1,4-diaza-spiro[4.5]dec-1-ene 
• 14838-15-4 u-2-amino-1-phenylpropan-1-ol 
• 51714-48-8 2-Bromo-N-(1-methyl-2-oxo-2-phenyl-ethyl)-propionamide 
• 51714-54-6 N-(1-Methyl-2-oxo-2-phenyl-ethyl)-2,2-diphenyl-acetamide 
• 33124-11-7 4-methyl-5-phenyl-oxazol-2-ylamine 
• 51714-50-2 2,2-Dibromo-N-(1-methyl-2-oxo-2-phenyl-ethyl)-acetamide 
• 51714-49-9 2-Bromo-2-methyl-N-(1-methyl-2-oxo-2-phenyl-ethyl)-propionamide 
• 51714-52-4 2,2,2-Tribromo-N-(1-methyl-2-oxo-2-phenyl-ethyl)-acetamide 
• 51714-55-7 N-(1-Methyl-2-oxo-2-phenyl-ethyl)-2,2,2-triphenyl-acetamide 
• 51714-51-3 2,2-Dibromo-N-(1-methyl-2-oxo-2-phenyl-ethyl)-propionamide 
• 51714-46-6 N-(1-Methyl-2-oxo-2-phenyl-ethyl)-propionamide 
• 52028-46-3 2-pivaloylamino-1-phenyl-1-propanone 
• 16735-28-7 N-(1-methyl-2-oxo-2-phenylethyl)acetamide 

Relevant articles and documents

HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME

A heterocyclic compound represented by formula XI, a pharmaceutically acceptable salt, a solvate, or a solvate of a pharmaceutically acceptable salt thereof, use thereof, and a composition containing the same. The compound is novel in structure and has good STAT5 inhibitory activity.

Synthesis of 2-Amino Substituted Oxazoles from α-Amino Ketones and Isothiocyanates via Sequential Addition and I2-Mediated Desulfurative Cyclization

Oxazol-2-amines were synthesized by annulation of α-amino ketones and isothiocyanates. This sequential synthetic process involves addition of α-amino ketones to isothiocyanates and I2-promoted desulfurative cyclization omitting isolation of the less stable thiourea intermediates. It is transition metal-free and operationally simple, providing access to a variety of 2-amino substituted oxazole derivatives under mild reaction conditions. (Figure presented.).

5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation.