16748-29-1

Basic information

• Product Name: N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE
• Synonyms: H-L-MEORN-OH HCL;H-MEORN-OH HCL;N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE;N-ME-ORNITHINE HCL;N-ME-ORN-OH HCL;N-Me-Orn-OH;N2-Methyl-L-ornithine
• CAS NO: 16748-29-1
• Molecular Formula: C6H15ClN2O2
• Molecular Weight: 182.65
• Product Categories: amino acids
• Mol File: 16748-29-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Store at RT.
• CAS DataBase Reference: N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE(16748-29-1)
• EPA Substance Registry System: N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE(16748-29-1)

Safety Data

• Hazardous Substances Data: 16748-29-1(Hazardous Substances Data)

Usage

General Description

N-Alpha-methyl-L-ornithine hydrochloride is a chemical compound that is used in scientific research and pharmaceutical development. It is a derivative of the amino acid ornithine and is often used as an inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. By blocking this enzyme, N-alpha-methyl-L-ornithine hydrochloride can help regulate the production of polyamines, which are important for cell growth and proliferation. N-ALPHA-METHYL-L-ORNITHINE HYDROCHLORIDE has shown potential in cancer treatment research, as well as in the study of various metabolic and neurological disorders. Additionally, it has been investigated for its potential use in preventing tropical diseases such as African sleeping sickness.

Upstream product

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• 13726-85-7 Boc-Gln-OH 
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• 3304-51-6 N-carboxybenzyl-L-ornithine 
• 34605-48-6 N^α-Acetyl-N^α-tosyl-L-ornithine-isopropylester 
• 15647-43-5 N^δ-benzoyl-L-ornithine 
• 880145-14-2 N⁵-benzoyl-N²-(toluene-4-sulfonyl)-L-ornithine 
• 37149-04-5 N^α-Benzyl-N^α-methyl-N^ε-tosyl-l-ornithin 

Relevant articles and documents

Synthesis of cyclic and acyclic Nα-methyl-Nω-alkyl-L-arginine analogues

A series of Nα-methyl-alkyl-L-arginine (Arg) analogues have been synthesized from inexpensive, commercially available starting materials. These analogues, once incorporated into pharmaceutically relevant peptides, are expected to increase binding affinity, receptor selectivity, lipophilicity, and stability as demonstrated with analogues of similar design and structure.

Stoffwechselprodukte von Mikroorganismen. Maduraferrin, ein neuartiger Siderophor aus Actinomadura madurae

Maduraferrin, a Novel Siderophore from Actinomadura madurae.From a strain of Actinomadura madurae, a new siderophore was isolated.Maduraferrin is the Fe complex of an oligopeptide composed of salicylic acid, β-alanine, glycine, L-serine, Nδ-hydroxy-Nα-methyl-L-ornithine, and L-hexahydropyridazine-3-carboxylic acid.The complexing centers are a salicylamide moiety, a hydroxamic-acid group and an acid hydrazide group.