16754-73-7 Usage
Description
Tert-Butyl 3-bromo-2-oxopropanoate is an organic compound that belongs to the class of esters. It is characterized by the presence of a tert-butyl group, a bromine atom, and an ester functional group. tert-Butyl 3-bromo-2-oxopropanoate is known for its reactivity and is often utilized in various chemical reactions and synthesis processes.
Uses
Used in Pharmaceutical Industry:
Tert-Butyl 3-bromo-2-oxopropanoate is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the formation of complex molecules that can be used as potential drug candidates.
Used in Chemical Research:
In the field of chemical research, tert-Butyl 3-bromo-2-oxopropanoate serves as a valuable starting material for the preparation of various organic compounds. Its reactivity and functional groups make it a versatile building block for creating a wide range of molecules.
Used in Peptide Synthesis:
Tert-Butyl 3-bromo-2-oxopropanoate is used as a key component in the study of preparing macrocyclic peptides from thiazole amino acids. Its incorporation into the peptide structure can lead to the development of novel bioactive compounds with potential applications in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 16754-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,5 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16754-73:
(7*1)+(6*6)+(5*7)+(4*5)+(3*4)+(2*7)+(1*3)=127
127 % 10 = 7
So 16754-73-7 is a valid CAS Registry Number.
16754-73-7Relevant articles and documents
Dienamine-mediated inverse-electron-demand hetero-diels-alder reaction by using an enantioselective H-bond-directing strategy
Albrecht, Lukasz,Dickmeiss, Gustav,Weise, Christian F.,Rodriguez-Escrich, Carles,Jorgensen, Karl Anker
supporting information, p. 13109 - 13113 (2013/02/26)
The first H-bond-directed inverse-electrondemand hetero-Diels-Alder reaction proceeding via a dienamine intermediate was developed. Under optimized reaction conditions, the corresponding dienamine species underwent regio- and stereoselective functionalization at the remote double bond, five bonds away from the stereogenic center of the catalyst, to give dihydropyran derivatives bearing three contiguous stereogenic centers. High stereoselectivities were obtained by employing a bifunctional squaramide-containing aminocatalyst, and the rationalization for the stereochemical outcome of the reaction was provided. Furthermore, the possibility to employ the introduced chiral framework for the synthesis of tetrahydropyrans as well as polycyclic compounds was demonstrated.