1678-49-5 Usage
Description
3-Bromo-4-nitropyridine N-oxide is a chemical compound characterized by the presence of a bromine atom at the 3rd position and a nitro group at the 4th position on a pyridine ring, with an N-oxide functional group. It is a versatile intermediate in various chemical reactions and synthesis processes.
Uses
Used in Organic Synthesis:
3-Bromo-4-nitropyridine N-oxide is used as a key intermediate for the synthesis of various organic compounds. Its unique structure allows for a range of reactions, such as nucleophilic substitution, electrophilic aromatic substitution, and reductive dehalogenation, making it a valuable building block in organic chemistry.
Used in Pharmaceutical Industry:
3-Bromo-4-nitropyridine N-oxide is used as a starting material for the development of new pharmaceuticals. Its reactivity and structural features enable the creation of diverse drug candidates with potential therapeutic applications, including the treatment of various diseases and disorders.
Used in Agrochemical Industry:
3-Bromo-4-nitropyridine N-oxide is employed as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the development of effective compounds that can protect crops and control pests, contributing to increased agricultural productivity.
Used in Dye Industry:
3-Bromo-4-nitropyridine N-oxide is utilized as a raw material in the production of dyes and pigments. Its ability to undergo various chemical reactions enables the synthesis of a wide range of colored compounds, which can be used in various applications, such as textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 1678-49-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,7 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1678-49:
(6*1)+(5*6)+(4*7)+(3*8)+(2*4)+(1*9)=105
105 % 10 = 5
So 1678-49-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3BrN2O3/c6-4-3-7(9)2-1-5(4)8(10)11/h1-3H
1678-49-5Relevant articles and documents
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
Huang, Ya-Yao,Chiu, Ming-Jang,Yen, Ruoh-Fang,Tsai, Chia-Ling,Hsieh, Hao-Yu,Chiu, Ching-Hung,Wu, Chi-Han,Hsin, Ling-Wei,Tzen, Kai-Yuan,Cheng, Cheng-Yi,Ma, Kuo-Hsing,Shiue, Chyng-Yann
, (2019/08/01)
[18F]T807 is a potent tau protein imaging agent. In order to fulfill the demand from preclinical and clinical studies, we developed an automated one-pot two-step synthesis of this potent tau imaging agent and studied its stability, and dosimetr
Synthesis of dicationic carbazole and 4′-amino-(3,3'-bipyridine)-4-ol and the spectral characteristics of carbazoles
Wang,Li,Ye,Guo,Jia
, p. 4632 - 4636 (2013/07/25)
The dicationic carbazole compound, 3,6-dimethyl-3,6-diazacarbazole diiodide (8) was prepared with 3-bromopyridine as a starting material by a six-step synthesis. The intermediates and target compound were confirmed by IR, NMR and MS. Meanwhile, UV-visible and fluorescent characteristics of 3,6-diazacarbazole (7) and 3,6-dimethyl-3,6-diazacarbazole diiodide (8) were investigated. It was found that fluorescence decay over time of dicationic carbazole existed in low ionic strength and high ionic strength could stabilize the fluorescence of dicationic carbazole.
Pyridine analogues of nimesulide: Design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors
Renard, Jean-Fran?ois,Arslan, Deniz,Garbacki, Nancy,Pirotte, Bernard,De Leval, Xavier
supporting information; experimental part, p. 5864 - 5871 (2010/02/28)
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most prescribed medications, although the chronic use of such pharmacological agents is commonly associated with numerous side effects. The demonstration that the use of COX-2 selective or