167886-87-5Relevant articles and documents
Palladium-catalyzed intermolecular aminocarbonylation of alkenes: Efficient access of β-amino acid derivatives
Cheng, Jiashun,Qi, Xiaoxu,Li, Ming,Chen, Pinhong,Liu, Guosheng
supporting information, p. 2480 - 2483 (2015/03/04)
A novel palladium-catalyzed intermolecular aminocarbonylation of alkenes has been developed in which the employment of hypervalent iodine reagent can accelerate the intermolecular aminopalladation, which thus provides the successful catalytic transformation. The current transformation presents one of the most convenient methods to generate β-amino acid derivatives from simple alkenes.
Cyclic amides
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, (2008/06/13)
Cyclic amides are inhibitors of tumor necrosis factor and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 3-phenyl-3-(1-oxoisoindolin-2-yl)propionamide.