1681-24-9 Usage
Description
Dibromoacetyl bromide, with the chemical formula C2H2Br2O, is a colorless to light yellow liquid characterized by a pungent odor. It is a highly reactive acylating agent that is widely utilized in organic synthesis, particularly for the preparation of pharmaceuticals and agricultural chemicals.
Uses
Used in Pharmaceutical Industry:
Dibromoacetyl bromide is used as a reagent in the synthesis of various pharmaceutical compounds. Its high reactivity allows it to participate in acylation and bromination reactions, which are crucial for the production of a range of medications.
Used in Agricultural Chemical Industry:
In the agricultural sector, dibromoacetyl bromide serves as a key component in the creation of agrochemicals. Its ability to undergo diverse chemical reactions makes it an essential tool in developing effective products for crop protection and other agricultural applications.
Safety Precautions:
Due to its corrosive nature, dibromoacetyl bromide can cause severe skin and eye irritation. It is also highly flammable and can release toxic fumes when heated. Therefore, it is imperative to handle this chemical compound with extreme care, using appropriate safety measures to prevent accidents and health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 1681-24-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,8 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1681-24:
(6*1)+(5*6)+(4*8)+(3*1)+(2*2)+(1*4)=79
79 % 10 = 9
So 1681-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C2HBr3O/c3-1(4)2(5)6/h1H
1681-24-9Relevant articles and documents
Liquid-phase oxidation of bromovinyl compounds with molecular oxygen
Bayatyan,Bayatyan,Saakyan
, p. 1849 - 1852 (2006)
Liquid-phase oxidation of bromovinyl compounds with the aim to obtain the corresponding α-bromo acids was studied.
STEREOCHEMICAL OBSERVATIONS IN THE SYNTHESIS OF NOVEL 1,4,5,9b-TETRAHYDRO-5-PHENYL-2H-AZETOIOSQUINOLIN-2-ONE DERIVATIVES
Nortey, Samuel O.,McComsey, David F.,Maryanoff, Bruce E.
, p. 1075 - 1088 (2007/10/02)
Imine (5) reacted with Cl2CHC(O)Cl in the presence of Et3N to give β-lactams (7a) and (7b) in a 4:1 ratio.The stereochemistry of cycloadduct (7a) was confirmed by X-ray analysis.Uncyclized intermediates were identified.Reduction of dichloro β-lactam (7a) with Zn/HOAc gave mostly exo monochloride (13a), with high stereoselectivity (10:1 ratio).Reduction of a mixture of exo and endo monochlorides (13a) and (13b) with Zn/HOAc indicated that the more sterically hidered endo chlorine is preferentially attacked.Reduction of (7a) with Bu3SnH gave β-lactam (14a) as the major product.
