168111-92-0 Usage
Description
(5R)-5-hydroxypyrrolidin-2-one, also known as L-pyroglutamic acid or L-pyrrolidone carboxylic acid, is a naturally occurring chemical compound that is found in high concentrations in human plasma and urine. It is a cyclic derivative of the amino acid glutamine and plays a role in various physiological processes in the body.
Uses
Used in Skincare and Cosmetic Products:
(5R)-5-hydroxypyrrolidin-2-one is used as a moisturizing and anti-aging agent in skincare and cosmetic products due to its ability to improve skin hydration and reduce the appearance of fine lines and wrinkles.
Used in Pharmaceutical Applications:
(5R)-5-hydroxypyrrolidin-2-one is used as a potential cognitive enhancer and memory improver, as it has been studied for its potential role in improving cognitive function and memory.
Used in Food Additives:
(5R)-5-hydroxypyrrolidin-2-one is used as a potential antioxidant and neuroprotective agent in food additives, as it has been researched for its potential applications in this area.
Used in Research:
(5R)-5-hydroxypyrrolidin-2-one is used as a subject of research for its potential applications in pharmaceuticals and other industries, as it has been studied for its various physiological properties and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 168111-92-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,1,1 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 168111-92:
(8*1)+(7*6)+(6*8)+(5*1)+(4*1)+(3*1)+(2*9)+(1*2)=130
130 % 10 = 0
So 168111-92-0 is a valid CAS Registry Number.
168111-92-0Relevant articles and documents
A simple synthesis of bannucine and 5′-epibannucine from (-)-vindoline
Ilkei, Viktor,Bana, Péter,Tóth, Flórián,Palló, Anna,Holczbauer, Tamás,Czugler, Mátyás,Sánta, Zsuzsanna,Dékány, Miklós,Szigetvári, áron,Hazai, László,Szántay, Csaba,Szántay, Csaba,Kalaus, Gy?rgy
, p. 9579 - 9586 (2015)
Bannucine is an Aspidosperma alkaloid isolated from the dried leaves of Catharanthus roseus. The molecule is a derivative of vindoline bearing a C10 substituent, a pattern common to the antineoplastic dimeric indole alkaloids of C. roseus. In bannucine, a 2-pyrrolidone moiety is attached at C5′ to the aromatic ring of the vindoline core at C10. In the present work we report the synthesis of bannucine and its 5′-epimer from natural (-)-vindoline using a cyclic N-acyliminium ion intermediate whose N-acylaminocarbinol precursor is synthesized by the partial reduction of succinimide. We also describe the separation and the structural analysis of the two epimers, using among others, single crystal X-ray diffraction methods, in order to clarify the orientation of the proton attached to the C5′ carbon. The in vitro antineoplastic activity of the pure epimers was also investigated, but none of the two substances showed significant activity on the examined tumour cell lines.
