16814-81-6 Usage
Description
(S)-5-Amino-2-hydroxypentanoic acid, also known as L-Norvaline, is a non-proteinogenic amino acid that is naturally found in small quantities in various foods. It has been identified for its potential bioactive properties, particularly its ability to inhibit enzymes that break down nitric oxide, which may lead to increased levels of nitric oxide in the body.
Uses
Used in Athletic Performance Enhancement:
(S)-5-Amino-2-hydroxypentanoic acid is used as a supplement for athletes and bodybuilders to improve blood flow and muscle function. The increased levels of nitric oxide resulting from the inhibition of its breakdown can enhance athletic performance and muscle recovery.
Used in Pharmaceutical Applications:
L-Norvaline is used as a potential therapeutic agent for its anti-inflammatory and antioxidant properties. It is being studied for further research in the fields of medicine and nutrition, with possible applications in treating various conditions related to inflammation and oxidative stress.
Used in Nutritional Supplements:
(S)-5-Amino-2-hydroxypentanoic acid is used as an ingredient in nutritional supplements, aiming to provide health benefits related to improved blood flow, muscle function, and overall well-being. Its potential anti-inflammatory and antioxidant properties also contribute to its value in the nutritional supplement industry.
Check Digit Verification of cas no
The CAS Registry Mumber 16814-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,1 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 16814-81:
(7*1)+(6*6)+(5*8)+(4*1)+(3*4)+(2*8)+(1*1)=116
116 % 10 = 6
So 16814-81-6 is a valid CAS Registry Number.
16814-81-6Relevant articles and documents
CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS
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Page/Page column 116-117, (2012/11/07)
Conformationally restricted, spatially defined 12-30 membered macrocyclic ring systems of formulae Ia and Ib are constituted by three distinct molecular parts: Template A, conformation Modulator B and Bridge C. These macrocycles Ia and Ib are readily manufactured by parallel synthesis or combinatorial chemistry in solution or on solid phase. They are designed to interact with a variety of specific biological target classes, examples being the agonistic or antagonistic activity on G-protein coupled receptors (GPCRs), ion channels and signal transduction pathways. In particular, these macrocycles act as antagonists of the motilin receptor, the FP receptor and the purinergic receptors P2Y1, as modulators of the serotonin receptor of subtype 5-HT2B, as blockers of the voltage-gated potassium channel Kv1.3 and as inhibitors of the β-catenin-dependent “canonical” Wnt pathway. Thus they are showing great potential as medicaments for a variety of diseases.
(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]- -proline, a novel orally active inhibitor of ACE
Karanewsky,Badia,Cushman,DeForrest,Dejneka,Loots,Perri,Petrillo Jr.,Powell
, p. 204 - 212 (2007/10/02)
The synthesis of a series of orally active, phosphinyloxyacyl proline inhibitors of angiotensin converting enzyme (ACE) is described. The in vitro and in vivo ACE inhibitory activities are reported for each compound. The structure-activity relationship fo
