16879-90-6

Basic information

• Product Name: N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt
• Synonyms: CBZ-TYR(TBU)-OH DCHA;BENZYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE DICYCLOHEXYLAMINE SALT;N-BENZYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE (DICYCLOHEXYLAMMONIUM) SALT;N-ALPHA-CARBOBENZOXY-O-T-BUTYL ETHER L-TYROSINE DICYCLOHEXYLAMMONIUM SALT;N-ALPHA-CBZ-O-T-BUTYL-L-TYROSINE DICYCLOHEXYLAMMONIUM SALT;N-ALPHA-BENZYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE DICYCLOHEXYLAMINE;N-ALPHA-BENZYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE DICYCLOHEXYLAMINE;N-Z-O-TERT-BUTYL-L-TYROSINE DICYCLOHEXYLAMINE SALT
• CAS NO: 16879-90-6
• Molecular Formula: C₁₂H₂₃N*C₂₁H₂₅NO₅
• Molecular Weight: 552.74
• EINECS: 240-910-7
• Product Categories: Tyrosine [Tyr, Y];Z-Amino Acids and Derivatives;Z-Amino acid series
• Mol File: 16879-90-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 158-161 °C
• Boiling Point: 556.8 °C at 760 mmHg
• Flash Point: 290.5 °C
• Appearance: white powder
• Density: 1.185 g/cm³
• Vapor Pressure: 3.12E-13mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt(16879-90-6)
• EPA Substance Registry System: N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt(16879-90-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 16879-90-6(Hazardous Substances Data)

Usage

Description

N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt, also known as Z-Tyr(tBu)-OH DCHA, is a protected form of L-tyrosine (T899975) characterized by its white to off-white powder appearance. It is a chemical compound utilized in the solid-phase synthesis of potential vaccines, specifically those that are dendrimers composed of a lysyllysine core and a glycopeptide antigen.

Uses

Used in Pharmaceutical Industry:
N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt is used as a key component in the solid-phase synthesis for the development of potential vaccines. Its application is crucial for creating dendrimers with a lysyllysine core and a glycopeptide antigen, which are essential for enhancing the immune response against various diseases.
Used in Vaccine Development:
N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt is used as a building block in the creation of dendrimers for vaccine development. The compound plays a vital role in the synthesis process, allowing for the formation of complex structures that can effectively target specific pathogens and improve the overall efficacy of the vaccine.
Used in Research and Development:
In addition to its applications in the pharmaceutical industry, N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt is also utilized in research and development settings. Scientists and researchers employ this compound to study its properties and potential applications in various fields, including drug discovery, biochemistry, and molecular biology.

InChI:InChI=1/C21H25NO5.C12H23N/c1-21(2,3)27-17-11-9-15(10-12-17)13-18(19(23)24)22-20(25)26-14-16-7-5-4-6-8-16;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-12,18H,13-14H2,1-3H3,(H,22,25)(H,23,24);11-13H,1-10H2

Downstream Products

• 343631-38-9 C₁₄H₂₁NO₃ 
• 1799443-50-7 N-fluorenylmethoxycarbonyl-O-tertbutyl N-methyltyrosine 
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• 1082954-37-7 (S)-N-((S)-1-amino-3-(4-tert-butoxyphenyl)-1-oxopropan-2-yl)-2-(3-phenylthioureido)propanamide 
• 1082954-31-1 (S)-2-amino-N-((S)-1-amino-3-(4-t-butoxyphenyl)-1-oxopropan-2-yl)propanamide 
• 39894-76-3 (S)-benzyl-1-amino-3-(4-t-butoxyphenyl)-1-oxopropan-2-ylcarbamate 
• 1073755-06-2 Z-Tyr(tBu)-Abd tert-butyl ester 
• 74085-40-8 [(S)-1-{(R)-1-[({[(S)-1-Benzyl-2-oxo-2-(N'-propionyl-hydrazino)-ethyl]-methyl-carbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-tert-butoxy-phenyl)-ethyl]-methyl-carbamic acid benzyl ester 
• 74085-41-9 (S)-N-{(R)-1-[({[(S)-1-Benzyl-2-oxo-2-(N'-propionyl-hydrazino)-ethyl]-methyl-carbamoyl}-methyl)-carbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-2-methylamino-propionamide 
• 61342-91-4 Tyr(tBu)-Pro-O-tBu 
• 874190-42-8 Z-Leu-Val-Val-Tyr-Pro 
• 874190-41-7 Val-Val-Tyr(tBu)-Pro-O-tBu 
• 61342-76-5 Z-Tyr(tBu)-Pro-O-tBu