169315-44-0

Basic information

• Product Name: Ethanone, 2-azido-1-(4-hydroxyphenyl)-
• CAS NO: 169315-44-0
• Molecular Formula: C8H7N3O2
• Molecular Weight: 177.162
• Mol File: 169315-44-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-azido-1-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-azido-1-(4-hydroxyphenyl)-(169315-44-0)
• EPA Substance Registry System: Ethanone, 2-azido-1-(4-hydroxyphenyl)-(169315-44-0)

Safety Data

• Hazardous Substances Data: 169315-44-0(Hazardous Substances Data)

Usage

Description

Ethanone, 2-azido-1-(4-hydroxyphenyl)-, also known as ethanone-4-hydroxyphenyl-azide, is a chemical compound characterized by the molecular formula C9H8N4O2. This yellow powder is a significant reagent in the realm of organic synthesis and chemical research, with its potential extending into medicinal chemistry for the development of pharmaceutical drugs. Additionally, it finds applications in the production of polymers and dyes. However, due to its sensitivity to shock and heat, as well as its potential to cause skin irritation and respiratory issues, careful handling is paramount.

Uses

Used in Organic Synthesis:
Ethanone, 2-azido-1-(4-hydroxyphenyl)is utilized as a reagent in organic synthesis for its unique chemical properties that facilitate various chemical reactions and the formation of new compounds.
Used in Medicinal Chemistry:
In the pharmaceutical industry, this compound serves as a key intermediate in the development of drugs, leveraging its chemical structure to contribute to the creation of novel therapeutic agents.
Used in Polymer Production:
Ethanone, 2-azido-1-(4-hydroxyphenyl)is employed in the production of polymers, where its chemical composition aids in the synthesis of polymeric materials with specific properties.
Used in Dye Manufacturing:
Ethanone, 2-azido-1-(4-hydroxyphenyl)is also used in the manufacturing of dyes, capitalizing on its color-producing capabilities to create a range of dye products for various applications.

Upstream product

• 6305-04-0 p-hydroxyphenacyl chloride 
• 99-93-4 4-Hydroxyacetophenone 
• 2200-91-1 4-ethynylphenol 
• 2491-38-5 2-bromo-1-(4'-hydroxyphenyl)-1-ethanone 

Downstream Products

• 77369-38-1 2-amino-1-(4-hydroxyphenyl)ethyl ketone 
• 344359-54-2 N-[2-(4-hydroxyphenyl)-2-oxoethyl]acetamide 
• 344359-55-3 2-amino-4-(4-hydroxy-phenyl)-1H-pyrrole-3-carbonitrile 
• 344359-59-7 4-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol 
• 344427-71-0 N-[3-cyano-4-(4-hydroxy-phenyl)-1H-pyrrol-2-yl]-formamidine 
• 1427301-52-7 (R)-2-{4-[(S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-(4-hydroxyphenyl)ethanol 
• 156-38-7 4-hydroxyphenylacetate 
• 623-05-2 (4-hydroxyphenyl)methanol 

Relevant articles and documents

Highly Efficient Multiple-Labeling Probes for the Visualization of Enzyme Activities

Quinone methide (QM) as a latent trapping unit has been widely explored in activity-based self-immobilizing reagents. However, further application of this strategy has been largely hampered by the limited labeling efficiency to proteins. In this study, a

Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity

A facile synthetic strategy has been developed for the generation of structurally diverse N-fused heterocycles. The formation of fused 1,2,3-triazole indolo and pyrrolodiazepines proceeds through an initial Knoevenagel condensation followed by intramolecu

Tetrahydro-benzofuran -4 - oxime-based triazole drug, preparation method and application thereof

The invention relates to a tetrahydrobenzofuran-4-ketoximetriazole medicine. The medicine is a cis-isomeride of tetrahydrobenzofuran-4-ketoximetriazole medicine, and also comprises pharmaceutically acceptable salts and derivatives of the tetrahydrobenzofuran-4-ketoximetriazole medicine. A preparation method of the tetrahydrobenzofuran-4-ketoximetriazole medicine comprises the following steps: preparing 3,6,6-trimethyl-6,7-dihydrobenzofuran-4(5H)-one (intermediate 1) and nitrine (intermediate 2), carrying out a condensation reaction to convert the intermediate 1 into cis-oxime (intermediate 3), separating, purifying, alkylating to obtain propargyl oxime ether (intermediate 4), and carrying out a copper catalyzed cycloaddition reaction on the intermediate 4 and the nitrine (intermediate 2) to synthesize 1,2,3-triazole substituted furocyclohexanone oxime and a derivative thereof. The above compounds have dual curative effects of antiulcer and stomach cancer resistance, and can be used in stomach cancer treatment as alternative medicines.