169447-78-3

Basic information

• Product Name: 1-tert-butoxycarbonyl-2(S)-n-butyl-4-(2,3-dimethylbenzoyl)piperazine
• Synonyms: 1-tert-butoxycarbonyl-2(S)-n-butyl-4-(2,3-dimethylbenzoyl)piperazine
• CAS NO: 169447-78-3
• Molecular Weight: 374.524
• Mol File: 169447-78-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-tert-butoxycarbonyl-2(S)-n-butyl-4-(2,3-dimethylbenzoyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butoxycarbonyl-2(S)-n-butyl-4-(2,3-dimethylbenzoyl)piperazine(169447-78-3)
• EPA Substance Registry System: 1-tert-butoxycarbonyl-2(S)-n-butyl-4-(2,3-dimethylbenzoyl)piperazine(169447-78-3)

Safety Data

• Hazardous Substances Data: 169447-78-3(Hazardous Substances Data)

Upstream product

• 169447-75-0 4-Benzyl-1-tert-butoxycarbonyl-2(S)-n-butylpiperazine 
• 169447-74-9 1-Benzyl-3(S)-n-butylpiperazine-2,5-dione 
• 175357-61-6 (S)-1-Benzyl-3-butyl-piperazine 
• 6404-28-0 Boc-Nle-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 169447-76-1 1-tert-butoxycarbonyl-2(S)-n-butylpiperazine 
• 603-79-2 2,3-dimethylbenzoic acid 

Downstream Products

• 169447-77-2 {(R)-1-[(S)-2-Butyl-4-(2,3-dimethyl-benzoyl)-piperazin-1-ylmethyl]-2-tritylsulfanyl-ethyl}-carbamic acid tert-butyl ester 
• 205679-66-9 ((S)-3-Butyl-piperazin-1-yl)-(2,3-dimethyl-phenyl)-methanone 

Relevant articles and documents

Inhibitors of farnesyl-protein transferase

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras. The compounds of formula A are representative of the compounds of the present invention: STR1