169774-69-0

Basic information

• Product Name: (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine
• Synonyms: (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine
• CAS NO: 169774-69-0
• Molecular Weight: 451.519
• Mol File: 169774-69-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine(169774-69-0)
• EPA Substance Registry System: (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine(169774-69-0)

Safety Data

• Hazardous Substances Data: 169774-69-0(Hazardous Substances Data)

Upstream product

• 10365-98-7 3-methoxyphenylboronic acid 
• 169774-63-4 (2S,3R)-1-Benzoyl-3-tert-butoxycarbonylmethyl-4-trifluoromethanesulfonyloxy-2,3-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 169774-61-2 (2S,3R)-1-benzoyl-3-tert-butoxycarbonylmethyl-4-oxopyrrolidine-2-carboxylic acid methyl ester 
• 169774-60-1 2S-N-benzoyl-2-methoxycarbonyl-4-(1-pyrrolidin)yl-<3,4>-dehydropyrrolidine 
• 169774-59-8 methyl (2S)-1-benzoyl-4-oxo-2-pyrrolidinecarboxylate 
• 98-88-4 benzoyl chloride 
• 31560-20-0 (2S,4R)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 

Downstream Products

• 169774-77-0 (2S,3S)-N-benzoyl-2-methoxycarbonyl-3-methoxycarbonylmethyl-4-(3-methoxyphenyl)-<4,5>-dehydropyrrolidine 
• 169774-85-0 (2S,3S,4R)-N-benzoyl-2-methoxycarbonyl-3-methoxycarbonylmethyl-4-(3-methoxyphenyl)pyrrolidine 
• 169774-81-6 (2S,3S,4S)-N-benzoyl-2-methoxycarbonyl-3-methoxycarbonylmethyl-4-(3-methoxyphenyl)pyrrolidine 
• 182502-51-8 (2S,3S,4S)-N-benzoyl-2-hydroxymethyl-3-tert-butoxycarbonylmethyl-4-(3-methoxyphenyl)pyrrolidine 
• 189573-94-2 (2S,3S)-1-Benzoyl-3-carboxymethyl-4-(3-methoxy-phenyl)-2,3-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 182502-45-0 [(2S,3S)-1-Benzoyl-2-hydroxymethyl-4-(3-methoxy-phenyl)-2,3-dihydro-1H-pyrrol-3-yl]-acetic acid tert-butyl ester 

Relevant articles and documents

Towards a versatile synthesis of kainoids I: Introduction of the C-3 and C-4 substituents

The first stages in the synthesis of acromelic acid analogues from trans-4-hydroxy-L-proline are described. An enamine alkylation was used to stereospecifically introduce the C-3 substituent, Grignard addition to a ketone or Pd(0) catalysed cross-coupling procedures adding C-4 aryl substituents for further manipulation. A number of versatile intermediates were generated.