170114-35-9

Basic information

• Product Name: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(pentafluorophenyloxy)-2(1H)-pyrimidinone
• Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(pentafluorophenyloxy)-2(1H)-pyrimidinone
• CAS NO: 170114-35-9
• Molecular Weight: 394.255
• Mol File: 170114-35-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(pentafluorophenyloxy)-2(1H)-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(pentafluorophenyloxy)-2(1H)-pyrimidinone(170114-35-9)
• EPA Substance Registry System: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(pentafluorophenyloxy)-2(1H)-pyrimidinone(170114-35-9)

Safety Data

• Hazardous Substances Data: 170114-35-9(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 951-78-0 2'-deoxyuridine 

Relevant articles and documents

Synthesis and anti-HIV activity of C4-modified pyrimidine nucleosides

One-pot syntheses provided a series of triazole- and pentafluorophenyloxy-substituted pyrimidine nucleosides. Most of the compounds in the series displayed anti-HIV activities but none as potent as AZT 2. 1-(β-D-Erythro-pentofuranosyl)-4-pentafluorophenyloxy-2(1H)-pyrimidinone 14 was the most potent and the most selective compound in the series with EC50 = 1.6 μM.