170161-19-0

Basic information

• Product Name: cyclobutyl phenyl sulfoxide
• Synonyms: cyclobutyl phenyl sulfoxide
• CAS NO: 170161-19-0
• Molecular Weight: 180.271
• Mol File: 170161-19-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cyclobutyl phenyl sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: cyclobutyl phenyl sulfoxide(170161-19-0)
• EPA Substance Registry System: cyclobutyl phenyl sulfoxide(170161-19-0)

Safety Data

• Hazardous Substances Data: 170161-19-0(Hazardous Substances Data)

Upstream product

• 67132-84-7 cyclobutyl phenyl sulfide 

Relevant articles and documents

Cyclobutyl phenyl sulfoxide and (SR)-cyclobutyl p-tolyl sulfoxide: New reagents for the spiroannelation of cyclopentanone

Cyclobutyl phenyl sulfide 2, cyclobutyl phenyl sulfoxide 3 and (SR)- cyclobutyl p-tolyl sulfoxide (SR)-8 have been synthesized and used for the spiroannelation of cyclopentanone. In the most effective sequence, lithiated 3 is added to ketones with formation of β-hydroxy sulfoxides 4a-g, which are ring enlarged and hydrolyzed to cyclopentanones 6a-e and sulfanylcyclopentene 6f, respectively, after reduction to β-hydroxy sulfides 5a-f. In an asymmetric version using (SR)-8, partial racemization during ring enlargement was observed.