17017-71-9 Usage
Description
1-Benzyl-1H-indole-2-carboxylic acid, also known as benzylindol-2-carboxylic acid, is a chemical compound with the molecular formula C19H15NO2. It is a derivative of indole and carboxylic acid, featuring a benzyl group attached to the indole ring. 1-benzyl-1H-indole-2-carboxylic acid is known for its structural and functional properties, which make it a versatile chemical with potential applications in various fields.
Uses
Used in Organic Synthesis:
1-Benzyl-1H-indole-2-carboxylic acid is used as a building block in organic synthesis for its ability to form a variety of complex organic molecules. Its unique structure allows for the creation of new compounds with potential applications in various industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-benzyl-1H-indole-2-carboxylic acid is used as a precursor for the development of new pharmaceuticals. Its potential biological activities, such as antimicrobial, antifungal, and anti-inflammatory effects, make it a promising candidate for drug development.
Used in Pharmaceutical Industry:
1-Benzyl-1H-indole-2-carboxylic acid is used as an active pharmaceutical ingredient for the treatment of various diseases and conditions. Its diverse biological activities contribute to its potential as a therapeutic agent in the development of new medications.
Used in Dye and Pigment Production:
Due to its aromatic and heterocyclic nature, 1-benzyl-1H-indole-2-carboxylic acid is used in the production of dyes and pigments. Its chemical properties allow for the creation of vibrant and stable colorants for use in various applications, such as textiles, plastics, and printing inks.
Overall, 1-benzyl-1H-indole-2-carboxylic acid is a versatile chemical compound with a wide range of potential applications across different industries, including organic synthesis, medicinal chemistry, pharmaceuticals, and dye and pigment production. Its unique structure and functional properties make it a valuable asset in the development of new and innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 17017-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,0,1 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 17017-71:
(7*1)+(6*7)+(5*0)+(4*1)+(3*7)+(2*7)+(1*1)=89
89 % 10 = 9
So 17017-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO2/c18-16(19)15-10-13-8-4-5-9-14(13)17(15)11-12-6-2-1-3-7-12/h1-10H,11H2,(H,18,19)
17017-71-9Relevant articles and documents
Calcium-Catalyzed Formal [5 + 2] Cycloadditions of Alkylidene β-Ketoesters with Olefins: Chemodivergent Synthesis of Highly Functionalized Cyclohepta[ b]indole Derivatives
Parker, Ariel N.,Martin, M. Cynthia,Shenje, Raynold,France, Stefan
, p. 7268 - 7273 (2019/10/08)
The calcium-catalyzed, formal [5 + 2] cycloaddition of indolyl alkylidene β-ketoesters with mono- A nd disubstituted aryl olefins to form cyclohepta[b]indole derivatives has been established. Unanticipated chemodivergence with phenyl vinyl sulfide/ether revealed a double [5 + 2] cycloaddition cascade providing ethano-bridged cyclohepta[b]indoles. Overall, the method's highlights include: (1) use of a green, calcium-based catalyst (2.5 mol % loading); (2) reaction times under 1 h; (3) mild reaction conditions; (4) substrate-derived chemodivergence; (5) functional group tolerance; and (6) examples of derivatization.
Synthesis of new functionalized indoles based on ethyl indol-2-carboxylate
Boraei, Ahmed T. A.,El Ashry, El Sayed H.,Barakat, Assem,Ghabbour, Hazem A.
, (2016/04/20)
Successful alkylations of the nitrogen of ethyl indol-2-carboxylate were carried out using aq. KOH in acetone. The respective N-alkylated acids could be obtained without separating the N-alkylated esters by increasing the amount of KOH and water. The use of NaOMe in methanol led to transesterification instead of the alkylation, while the use of NaOEt led to low yields of the N-alkylated acids. Hydrazinolysis of the ester gave indol-2-carbohydrazide which then was allowed to react with different aromatic aldehydes and ketones in ethanol catalyzed by acetic acid. Indol-2-thiosemicarbazide was used in a heterocyclization reaction to form thiazoles. The new structures were confirmed using NMR, mass spectrometry and X-ray single crystal analysis.
Synthesis of 3,3-Dihalo-2-oxindoles from 2-Substituted Indoles via Halogenation–Decarboxylation/Desulfonamidation–Oxidation Process
Jiang, Xiaojian,Zhang, Feng,Yang, Junjie,Yu, Pei,Yi, Peng,Sun, Yewei,Wang, Yuqiang
supporting information, p. 3938 - 3942 (2016/12/30)
A novel one-pot reaction which combines halogenation, decarboxylation/desulfonamidation with oxidation has been developed. Diverse valuable 3,3-dihalo-2-oxindole compounds can be produced rapidly and safely with isolated yields of up to 98% under mild conditions. (Figure presented.).
