17046-24-1

Basic information

• Product Name: diethyl N-(oxomethylidene)aspartate
• CAS NO: 17046-24-1
• Molecular Formula: C₉H₁₃NO₅
• Molecular Weight: 215.2032
• Mol File: 17046-24-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 283.4°C at 760 mmHg
• Flash Point: 118.2°C
• Density: 1.16g/cm³
• Vapor Pressure: 0.00316mmHg at 25°C
• Refractive Index: 1.473
• CAS DataBase Reference: diethyl N-(oxomethylidene)aspartate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-(oxomethylidene)aspartate(17046-24-1)
• EPA Substance Registry System: diethyl N-(oxomethylidene)aspartate(17046-24-1)

Safety Data

• Hazardous Substances Data: 17046-24-1(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 16115-68-7 diethyl L-aspartate hydrochloride 
• 57471-70-2 diethyl N-benzyloxycarbonyl-(S)-aspartate 
• 24608-57-9 RS-aspartic acid diethyl ester hydrochloride 

Downstream Products

• 145943-84-6 N-phenylcarbamoyl-L-aspartic acid 
• 100135-89-5 N-(methyl-phenyl-carbamoyl)-aspartic acid 
• 97021-39-1 N-(benzylcarbamoyl)-aspartic acid, diethyl ester 

Relevant articles and documents

Hydantoin-free synthesis of peptide ester isocyanates, isothiocyanates, and dipeptidyl ureas: The application of zinc dust in a carbonylation procedure without base

Non-Schotten-Baumann conditions are described for the hydantoin-free synthesis of peptide ester isocyanates using activated zinc dust as a non-basic HCl scavenger. Also, the procedure gives no N-acylated products in the case of the conversion of amino acid and peptide amides into isocyanates. Georg Thieme Verlag Stuttgart · New York.