170623-28-6

Basic information

• Product Name: 4(3H)-Quinazolinone, 3-[(1S)-1-phenylethyl]-
• CAS NO: 170623-28-6
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 170623-28-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 3-[(1S)-1-phenylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 3-[(1S)-1-phenylethyl]-(170623-28-6)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 3-[(1S)-1-phenylethyl]-(170623-28-6)

Safety Data

• Hazardous Substances Data: 170623-28-6(Hazardous Substances Data)

Upstream product

• 118-48-9 isatoic anhydride 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 122-51-0 orthoformic acid triethyl ester 
• 783371-72-2 2-amino-N-[(S)-α-methylbenzyl]-benzamide 

Downstream Products

• 823190-79-0 (4aS,8aS)-3-[(S)-α-methylbenzyl]-1,2,4a,5,6,7,8,8a-octahydroquinazolin-4-one 
• 823190-78-9 (4aR,8aR)-3-[(S)-α-methylbenzyl]-1,2,4a,5,6,7,8,8a-octahydroquinazolin-4-one 
• 5691-19-0 rac-trans-2-aminocyclohexanecarboxylic acid 
• 189101-41-5 (1S,2R)-(+)-2-aminocyclohexane-1-carboxylic acid 
• 189101-43-7 (1R,2S)-(-)-2-aminocyclohexane-1-carboxylic acid 
• 5691-19-0 (1R,2R)-2-aminocyclohexanecarboxylic Acid 

Relevant articles and documents

Synthesis, NMR and crystallographic studies of 2-substituted dihydroquinazolinones derived from (S)-phenylethylamine

2,3-Dihydro-3-[(S)-1-phenethyl]quinazolinone and some new 2-substituted derivatives bearing isopropyl, o-nitrophenyl and p-nitrophenyl groups were prepared in 40-90% yield by amidation of isatoic anhydride with (S)-phenylethylamine, followed by condensati

Synthesis of enantiopure cis- and trans-2-aminocyclohexane-1-carboxylic acids from octahydroquinazolin-4-ones

The chemoselective and diastereoselective hydrogenation of 2,3-dihydro-3-[(S)-α-methylbenzyl]-4-quinazolinone 2 affords octahydroquinazolinones cis-3 and cis-4. Epimerization of cis-3 and cis-4 using t-BuO-K+ produces trans-5 and tra