170787-99-2

Basic information

• Product Name: Efaproxiral sodium
• Synonyms: EFAPROXIRAL SODIUM;Sodium 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoate;2-[4-[2-(3,5-Dimethylphenylamino)-2-oxoethyl]phenoxy]-2-methylpropionic acid;RSR-13;2-(4-(2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoic acid monosodium salt;Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl-, monosodium salt;Rsr 13 sodium;Unii-3L83qp52xi
• CAS NO: 170787-99-2
• Molecular Formula: C20H22NNaO4
• Molecular Weight: 363.38275
• EINECS: 1806241-263-5
• Product Categories: Inhibitors
• Mol File: 170787-99-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 240.0 ~244.0 °C
• Boiling Point: 554.5 °C at 760 mmHg
• Flash Point: 289.2 °C
• Appearance: /
• Vapor Pressure: 3.93E-13mmHg at 25°C
• Solubility: ≥12.83 mg/mL in H2O with ultrasonic; ≥18.4 mg/mL in DMSO; ≥18.45 mg/mL in EtOH
• CAS DataBase Reference: Efaproxiral sodium(CAS DataBase Reference)
• NIST Chemistry Reference: Efaproxiral sodium(170787-99-2)
• EPA Substance Registry System: Efaproxiral sodium(170787-99-2)

Safety Data

• Hazardous Substances Data: 170787-99-2(Hazardous Substances Data)

Usage

Description

Efaproxiral sodium, also known as sodium pyruvate, is a synthetic compound that acts as an allosteric modifier of hemoglobin. It has the ability to stabilize and increase the oxygen affinity of hemoglobin, making it a promising candidate for various medical applications.

Uses

Used in Cardiovascular Applications:
Efaproxiral sodium is used as a treatment for cardiovascular conditions characterized by tissue hypoxia. By increasing the oxygen affinity of hemoglobin, it helps improve oxygen delivery to the tissues and organs, thereby alleviating the symptoms of hypoxia.
Used in Surgical Applications:
Efaproxiral sodium is used as an adjunctive treatment in surgical procedures, particularly those involving tissue hypoxia. It helps maintain adequate oxygen levels in the tissues during and after surgery, reducing the risk of complications and promoting faster recovery.
Used in Critical Care Applications:
Efaproxiral sodium is used in critical care settings to treat patients with severe tissue hypoxia, such as those with acute respiratory distress syndrome (ARDS) or sepsis. It helps improve oxygen delivery to the vital organs and tissues, supporting their function and survival.
Used in Radiation Therapy and Chemotherapy:
Efaproxiral sodium is used as an adjunctive treatment in standard radiation therapy and chemotherapy. It enhances the effectiveness of these treatments by increasing the oxygen supply to the tumor cells, making them more susceptible to the cytotoxic effects of radiation and chemotherapy. This can lead to improved treatment outcomes and reduced side effects for patients.

InChI:InChI=1/C20H23NO4.Na/c1-13-9-14(2)11-16(10-13)21-18(22)12-15-5-7-17(8-6-15)25-20(3,4)19(23)24;/h5-11H,12H2,1-4H3,(H,21,22)(H,23,24);/q;+1/p-1