17178-01-7

Basic information

• Product Name: 4-Chloro-2-methylbenzenethiol
• Synonyms: 4-Chloro-2-methylbenzenethiol
• CAS NO: 17178-01-7
• Molecular Formula: C₇H₇ClS
• Molecular Weight: 158.65
• Mol File: 17178-01-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 117 °C(Press: 21 Torr)
• Appearance: /
• Density: 1.217±0.06 g/cm3(Predicted)
• PKA: 6.32±0.48(Predicted)
• CAS DataBase Reference: 4-Chloro-2-methylbenzenethiol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-methylbenzenethiol(17178-01-7)
• EPA Substance Registry System: 4-Chloro-2-methylbenzenethiol(17178-01-7)

Safety Data

• Hazardous Substances Data: 17178-01-7(Hazardous Substances Data)

Upstream product

• 108-41-8 1-chloro-3-methylbenzene 
• 95-69-2 4-chloro-2-methylbenzeneamine 
• 94-76-8 (4-chloro-2-methyl-phenylsulfanyl)-acetic acid 
• 94-95-1 fast red TR 
• 7664-93-9 sulfuric acid 
• 56157-92-7 5-chloro-3-methylbenzene-2-sulphonyl chloride 
• 18619-15-3 [(2-Methylphenyl)sulfanyl]acetic acid 
• 624-92-0 Dimethyldisulphide 
• 106-48-9 4-chloro-phenol 

Downstream Products

• 103040-46-6 2-(4-chloro-2-methylphenylsulfanyl)propionic acid 
• 107775-79-1 benzyl(4-chloro-2-methylphenyl)sulfane 
• 86065-03-4 di-4-chloro-2-methylphenyl disulfide 
• 62838-91-9 2,2'-Dimethyl-4,4'-dichlordibenzolsulfenamid 
• 37779-91-2 C₁₄H₁₁Cl₂NO₄S₂ 
• 130220-08-5 2-(4-Chloro-2-methyl-phenylsulfanylmethyl)-[1,3]dioxolane 
• 21552-44-3 [2,5-Dichloro-4-(4-chloro-2-methyl-phenylsulfanylthiocarbonylamino)-phenyl]-dithiocarbamic acid 4-chloro-2-methyl-phenyl ester 
• 28953-41-5 3-(4-Chlor-2-methyl-phenylthio)-1,2-benzisothiazol 
• 94-76-8 (4-chloro-2-methyl-phenylsulfanyl)-acetic acid 
• 101292-41-5 1-(4-chloro-2-methyl-phenylsulfanyl)-2-(toluene-4-sulfonyl)-ethane 

Relevant articles and documents

Process for phenol alkylthiolation and its application to the synthesis of 4-acyl-2-alkylthiophenols

The invention relates to the preparation of alkylthiophenols by reaction of a dialkyl disulphide with a phenol. In the process according to the invention, the reaction is carried out in the presence of aluminum chloride or of ferric chloride in a solvent of the alkylbenzene type or, soley in the case of methylthiolation, in an excess of dimethyl disulphide. This process makes it possible, in particular to obtain, with a selectivity and in a yield which are excellent, 2-alkylthiophenols which may then be converted into 4-acyl-2-alkylthiophenols by means of a reaction at a temperature ranging from 40° to 100° C. with a complex BF3 :2RCOOH where R denotes an alkyl or propenyl radical, in a proportion of 10 to 15 moles of complex per mole of 2-alkylthiophenol.