17178-92-6

Basic information

• Product Name: Nitroterephthalsaeuredichlorid
• Synonyms: Nitroterephthalsaeuredichlorid
• CAS NO: 17178-92-6
• Molecular Weight: 248.022
• Mol File: 17178-92-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Nitroterephthalsaeuredichlorid(CAS DataBase Reference)
• NIST Chemistry Reference: Nitroterephthalsaeuredichlorid(17178-92-6)
• EPA Substance Registry System: Nitroterephthalsaeuredichlorid(17178-92-6)

Safety Data

• Hazardous Substances Data: 17178-92-6(Hazardous Substances Data)

Upstream product

• 104-85-8 para-methylbenzonitrile 
• 939-79-7 4-cyano-2-nitrotoluene 
• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 610-29-7 2-nitroterephthalic acid 

Downstream Products

• 14599-52-1 N¹,N⁴-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-2-nitroterephthalamide 
• 25906-68-7 (benzylthio)-terephthalic acid 
• 61220-65-3 (benzylthio)-terephthalyl chloride 
• 865375-93-5 6-ethynylindole 
• 137000-70-5 1,4-diethynyl-2-aminobenzene 
• 113639-27-3 1-nitro-2,5-diethynylbenzene 
• 899792-77-9 2-acetylamino-1,4-bis(3-morpholinoprop-1-ynyl)benzene 
• 899792-75-7 2-amino-1,4-bis(3-morpholinoprop-1-ynyl)benzene 
• 899792-72-4 1,4-bis(3-morpholinoprop-1-ynyl)-2-nitrobenzene 
• 899792-76-8 2-acetylamino-1,4-diethynylbenzene 
• 27391-37-3 2-aminoterephthalonitrile 
• 4193-70-8 2-nitrobenzene-1,4-dicarbonitrile 
• 50739-80-5 2-nitrobenzene-1,4-dicarboxamide 
• 61220-63-1 diisopropyl nitroterephthalate 

Relevant articles and documents

Direct mapping of local director field of nematic Liquid crystals at the nanoscale

Liquid crystals (LCs), owing to their anisotropy in molecular ordering, are of wide interest in both the display industry and soft matter as a route to more sophisticated optical objects, to direct phase separation, and to facilitate colloidal assemblies.

Water-induced fluorescence quenching of mono- and dicyanoanilines

Photophysical properties of monocyano- (2-, 3-, and 4-cyano) and dicyano- (3,4-, 3,5-, 2,3-, 2,4-, 2,5-, and 2,6-dicyano) anilines are investigated by fluorescence measurements. All the monocyanoanilines are virtually nonfluorescent in water (quantum yield 0.01); however, in nonaqueous solvents (cyclohexane, acetonitrile and ethanol), the fluorescence quantum yield is enhanced substantially. In contrast, dicyanoanilines investigated are highly fluorescent both in aqueous and nonaqueous environments. The photophysical data and MO calculations suggest that conformational changes in the amino group and variation of hydrogen-bonding interactions between the solute and solvent water upon electronic excitation are responsible for the water quenching in the monocyanoanilines.

Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drug temozolomide

A series of new imidazo[5,1-d]-1,2,3,5-tetrazinones with additional hydrogen-bonding or ionic substituents at the 8-carboxamide position of the antitumor drugs temozolomide (1) and mitozolomide (2) has been prepared. None of these compounds were significantly more cytotoxic in vitro against the mouse TLX5 lymphoma than the lead structures. Molecular modeling techniques have been used to design benzo- and pyrazolo[4,3-d]-1,2,3-triazinones bearing carboxamide groups in appropriate positions which are isosteric with temozolomide and mitozolomide but which cannot ring open to alkylating species. As predicted, these compounds have no inhibitory properties against human GM892A or Raji cell lines in vitro. Temozolomide and the spermidine- temozolomide conjugate 28 preferentially methylate guanines within guanine- rich sequences in DNA, but no experimental evidence has been found to support the hypothesis that such regions are involved in catalyzing the ring opening of the imidazotetrazinone prodrugs to their active forms.