1719-79-5 Usage
Description
20-ALPHA-DIHYDROCORTISOL, also known as 20α-dihydrocortisol, is a metabolite of cortisol, a hormone produced by the adrenal gland. It is a glucocorticoid, which is a type of corticosteroid, and plays a crucial role in the body's response to stress and maintaining homeostasis. Its primary functions include increasing blood sugar through gluconeogenesis, suppressing the immune system, and aiding in the metabolism of fat, protein, and carbohydrates.
Uses
Used in Pharmaceutical Industry:
20-ALPHA-DIHYDROCORTISOL is used as a topical corticosteroid for its anti-inflammatory and immunosuppressive properties. It is particularly effective in treating various skin conditions, such as eczema, dermatitis, and psoriasis, by reducing inflammation, redness, and itching.
Used in Endocrinology:
In the field of endocrinology, 20-ALPHA-DIHYDROCORTISOL is used as a diagnostic tool to assess adrenal gland function and the body's response to stress. It can help identify conditions related to cortisol imbalance, such as Cushing's syndrome or adrenal insufficiency.
Used in Metabolic Research:
20-ALPHA-DIHYDROCORTISOL is also used in metabolic research to study the role of glucocorticoids in regulating blood sugar levels, immune system function, and the metabolism of fat, protein, and carbohydrates. This research can contribute to the development of new treatments for metabolic disorders and conditions related to stress response.
Check Digit Verification of cas no
The CAS Registry Mumber 1719-79-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,1 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1719-79:
(6*1)+(5*7)+(4*1)+(3*9)+(2*7)+(1*9)=95
95 % 10 = 5
So 1719-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-18,22,24-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,17?,18+,19-,20-,21-/m0/s1
1719-79-5Relevant articles and documents
C-20 ketone reduction of hydrocortisone by rice field microalga Chlorella vulgaris MCCS 013
Ghasemi, Younes,Rasoul-Amini, Sara,Morowvat, Mohammad Hossein,Ghoshoon, Mohammad Bagher,Raee, Mohammad Javad,Khoubani, Soraya,Negintaji, Narges,Nouri, Fatemeh,Parvizi, Rezvan
, p. 824 - 828 (2009)
A unicellular microalga, Chlorella vulgaris, was isolated from rice field and applied in the biotransformation experiment of hydrocortisone (1). This strain has not been previously tested for hydrocortisone bioconversion. Fermentation was carried out in B
