172292-09-0Relevant articles and documents
Asymmetric Ring Cleavage Reaction Based on Crossed Aldol Condensation
Suemune, Hiroshi,Yoshida, Osamu,Uchida, Jun,Nomura, Yukiko,Tanaka, Masakazu,Sakai, Kiyoshi
, p. 7259 - 7262 (1995)
Ring cleavage reaction based on crossed aldol condensation of carbobicyclic ketones with benzaldehyde under acetalization conditions (BF3*Et2O/ethylene glycol) was studied.By using optically active 1,2-diols instead of ethylene glycol, an asymmetric version of this reaction could be developed for the first time.