17271-89-5Relevant articles and documents
Identification of Phenylphthalazinones as a New Class of Leishmania infantum Inhibitors
Sijm, Maarten,de Heuvel, Erik,Matheeussen, An,Caljon, Guy,Maes, Louis,Sterk, Geert-Jan,de Esch, Iwan J. P.,Leurs, Rob
, p. 219 - 227 (2020)
Leishmaniasis is a neglected parasitic disease caused by over 20 different Leishmania species. Current treatments often rely on harsh regimes of pentavalent antimonials such as sodium stibogluconate, while more recent drugs suffer other shortcomings such
An expedient and highly selective conversion of alcohols to azides using a NaN3/BF3·Et2O system
Kumar, H.M. Sampath,Reddy, B.V. Subba,Anjaneyulu,Yadav
, p. 7385 - 7388 (1998)
Alkyl azides were prepared in good yields by treatment of allylic and benzylic alcohols with a molar equivalent of NaN3 in the presence of BF3·Et2O in dioxane.
Application of magnetic dicationic ionic liquid phase transfer catalyst in nuclophilic substitution ractions of benzyl halides in water
Aghajeri, Manouchehr,Kiasat, Ali Reza,Goodajdar, Bijan Mombeni
, p. 1691 - 1695 (2016)
Magnetic dicationic ionic liquid (MDIL) was successfully prepared and evaluated as phase-transfer catalyst for nucleophilic substitution reactions. The reactions was occurred in water and furnished the corresponding benzyl derivatives in high yields. No evidence for the formation of by-product for example benzyl alcohol of the reaction was observed and the products were obtained in pure form without further purification.
Synthesis and Evaluation of Bakuchiol Derivatives as Potent Anti-inflammatory Agents in Vitro and in Vivo
Bai, Chunmei,Bian, Ming,Du, Huan-Huan,Gong, Guohua,Liu, Chunyan,Ma, Qianqian,Quan, Zhe-Shan,Wei, Chengxi
supporting information, p. 15 - 24 (2022/01/27)
Bakuchiol, a prenylated phenolic monoterpene derived from the fruit of Psoralen corylifolia L. (Buguzhi), is widely used to treat tumors, viruses, inflammation, and bacterial infections. In this study, we designed and synthesized 30 bakuchiol derivatives
Synthesis and comparison of in vitro dual anti-infective activities of novel naphthoquinone hybrids and atovaquone
Erasmus, Chané,Aucamp, Janine,Smit, Frans J.,Seldon, Ronnett,Jordaan, Audrey,Warner, Digby F.,N'Da, David D.
supporting information, (2021/07/06)
A principal factor that contributes towards the failure to eradicate leishmaniasis and tuberculosis infections is the reduced efficacy of existing chemotherapies, owing to a continuous increase in multidrug-resistant strains of the causative pathogens. Th