17377-13-8

Basic information

• Product Name: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)
• Synonyms: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI);2-AMINO-6-METHYL-7,8-DIHYDROPTERIDIN-4(1H)-ONE
• CAS NO: 17377-13-8
• Molecular Formula: C₇H₉N₅O
• Molecular Weight: 0
• Product Categories: PIPERIDINE
• Mol File: 17377-13-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 323.8°Cat760mmHg
• Flash Point: 149.6°C
• Appearance: /
• Density: 1.78g/cm³
• Vapor Pressure: 0.000256mmHg at 25°C
• Refractive Index: 1.842
• CAS DataBase Reference: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)(17377-13-8)
• EPA Substance Registry System: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)(17377-13-8)

Safety Data

• Hazardous Substances Data: 17377-13-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H9N5O/c1-3-2-9-5-4(10-3)6(13)12-7(8)11-5/h2H2,1H3,(H4,8,9,11,12,13)

Upstream product

• 708-75-8 2-amino-6-methylpteridin-4(1H)-one 
• 942-41-6 6-methyl-5,6,7,8-tetrahydrobopterin 
• 102069-94-3 6-methyldihydropterin hydrochloride 
• 120483-45-6 6-aminomethyl-7,8-dihydro-6H-pterin 
• 103422-18-0 C₇H₈⁽²⁾HN₅O 
• 120483-46-7 C₇H₉⁽²⁾HN₆O 
• 70786-93-5 6-methyl-5,6,7,8-tetrahydropterin 
• 583-63-1 ortoquinone 
• 70786-93-5 C₆⁽¹³⁾CH₉N₅O 
• 83387-39-7 C₆⁽¹³⁾CH₁₁N₅O₂ 

Downstream Products

• 73573-51-0 (S)-6-methyl-5,6,7,8-tetrahydropterin 
• 490-79-9 2,5-dihydroxybenzoic acid. 
• 708-75-8 2-amino-6-methylpteridin-4(1H)-one 

Relevant articles and documents

Phenylalanine Hydroxylase: Structural Determination of the Tetrahydropterin Intermediates by 13C NMR Spectroscopy

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The Synthesis of 6-Aminomethyl-5,6,7,8-tetrahydropterin

6-Aminomethyl-5,6,7,8-tetrahydropterin has been prepared by reduction of 2-acetamido-6-cyanopteridin-4(3H)-one to 2-acetamido-6-aminomethyl-5,6,7,8-tetrahydropteridin-4(3H)-one followed by acid hydrolysis.The hitherto undescribed 6-cyanopterin was prepared by careful hydrolysis of the 2-acetamido compound prepared by dehydration of the oxime derived from 2-acetamido-6-formylpteridin-4(3H)-one.The latter was prepared by selenium dioxide oxidation of the methyl compound.Oxidation of 6-aminomethyl-5,6,7,8-tetrahydropterin at neutral pH appears to proceed with significant side-chain loss in Tris buffer but not in phosphate buffer.

The dihydropteridine reductase (human brain) activity of some lipophilic quinonoid dihydropterins

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