173897-93-3 Usage
Description
(R)-benzyl 1-(4-(1H-pyrrolo[2,3-b]pyridin-4-ylcarbaMoyl)phenyl)ethylcarbaMate, also known as R-H157, is a potent and selective antagonist of the histamine H3 receptor. It is a significant therapeutic target for the treatment of cognitive disorders such as Alzheimer's disease and attention-deficit hyperactivity disorder (ADHD). R-H157 has been shown to improve cognitive function and memory in preclinical studies, making it a promising candidate for the development of new drugs for these conditions. It has also demonstrated the ability to enhance synaptic plasticity and neurotransmitter release in the brain, further highlighting its potential as a novel treatment for cognitive impairment.
Uses
Used in Pharmaceutical Industry:
(R)-benzyl 1-(4-(1H-pyrrolo[2,3-b]pyridin-4-ylcarbaMoyl)phenyl)ethylcarbaMate is used as a therapeutic agent for the treatment of cognitive disorders such as Alzheimer's disease and attention-deficit hyperactivity disorder (ADHD). It is employed for its ability to improve cognitive function and memory, as demonstrated in preclinical studies.
Used in Neurological Research:
(R)-benzyl 1-(4-(1H-pyrrolo[2,3-b]pyridin-4-ylcarbaMoyl)phenyl)ethylcarbaMate is used as a research tool to study the role of histamine H3 receptors in cognitive function and synaptic plasticity. Its ability to enhance neurotransmitter release in the brain makes it a valuable compound for investigating the underlying mechanisms of cognitive impairment and potential treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 173897-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,8,9 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 173897-93:
(8*1)+(7*7)+(6*3)+(5*8)+(4*9)+(3*7)+(2*9)+(1*3)=193
193 % 10 = 3
So 173897-93-3 is a valid CAS Registry Number.
173897-93-3Relevant articles and documents
VISUAL FUNCTION DISORDER IMPROVING AGENTS
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, (2016/09/12)
The present invention provides a visual function disorder improving agent containing a compound having Rho kinase inhibitory activity, particularly (R)-(+)-N-(1H-pyrrolo?2,3-büpyridin-4-yl)-4-(1-aminoethyl)benzamide, as an effective component. This agent
Benzamide compounds and pharmaceutical use thereof
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, (2008/06/13)
Benzamide compounds of the formula STR1 wherein each symbol is as defined in the specification, isomers thereof and pharmaceutically acceptable acid addition salts thereof. Pharmaceutical compositions comprising a therapeutically effective amount of this