174021-63-7 Usage
Description
[2-(5-Bromo-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester is a carbamate ester derivative with the molecular formula C14H18BrN2O2. It is synthesized from 5-bromo-1H-indole-3-ethylamine and 2-(tert-butoxycarbonylamino)ethanol, serving as a versatile building block in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
[2-(5-Bromo-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester is used as a precursor in the synthesis of new drugs for various therapeutic applications. Its unique structure allows for the development of innovative pharmaceutical compounds with potential benefits in treating different diseases.
Used in Organic Synthesis:
In the field of organic synthesis, [2-(5-Bromo-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester is utilized as a key intermediate for the creation of diverse chemical compounds. Its reactivity and functional groups enable the formation of a wide range of products, contributing to the advancement of chemical research and development.
Used in Drug Development:
[2-(5-Bromo-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester may have potential applications in the pharmaceutical industry for the development of new therapeutic agents. Its unique chemical properties and structural features make it a promising candidate for the design and synthesis of novel drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 174021-63-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,0,2 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 174021-63:
(8*1)+(7*7)+(6*4)+(5*0)+(4*2)+(3*1)+(2*6)+(1*3)=107
107 % 10 = 7
So 174021-63-7 is a valid CAS Registry Number.
174021-63-7Relevant articles and documents
Fradcarbazole A compound and preparation method and application thereof
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Paragraph 0015, (2019/07/01)
The invention discloses a fradcarbazole A compound and a preparation method and application thereof. The fradcarbazole A compound is prepared from staurosporine or halogenated staurosporine which is subjected to a sulfur acylation reaction, a salt forming reaction together with iodomethane, a substitution reaction and a dehydrating cyclization reaction. The fradcarbazole A compound has very high selectivity and inhibitory activity on acute myeloid cell strains, namely MV4-11, with Flt3-ITD mutation, has a weak inhibiting effect on human peripheral blood mononuclear cells (PBMC), and can be developed to be an efficient and low-toxicity drug for preventing and treating leukemia.
Preparation method of 5-bromoindole derivative
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, (2017/10/23)
The invention discloses a preparation method of a 5-bromoindole derivative tert-butyl 2-(5-bromo-1H-indole-3-yl)ethyl carbamate. The preparation method comprises the following steps: taking 5-bromoindole as an initial raw material, and performing a Friedel-Craft reaction, amidation, reduction and a tert-butyloxycarbonyl protection reaction to obtain the target product. The compound is an important medical intermediate compound.
INDOLE-DERIVED ARYLPIPERAZINES AS LIGANDS FOR 5HT1-LIKE, 5HT1B AND 5HT1D RECEPTORS
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, (2008/06/13)
Novel indole-derived azylpiperazines of general formula (I), wherein, inter alia, R 1 is NH 2 or NO 2, R' 1, R 2, R' 2, R 3 and R 4 are H, Z is--C--and X is 0. Methods for preparing such derivatives and the therapeutical uses thereof are also disclosed.
