174346-82-8 Usage
Description
2-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, also known as [1-(tert-Butoxycarbonyl)azetidin-2-yl]methanol, is a chemical compound with a unique structure that features a hydroxymethyl group and a tert-butyl ester group. It is characterized by its potential applications in the field of medical imaging and neuroscience.
Uses
Used in Medical Imaging:
2-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a potential positron emission tomography (PET) imaging agent for [application reason] the visualization and assessment of nicotinic acetylcholine receptors. This application is significant because it can help in the early detection and monitoring of various neurological disorders and conditions related to the nicotinic acetylcholine receptor system.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a key intermediate compound for the synthesis of various drugs and drug candidates. Its unique structure allows for the development of novel therapeutic agents that can target specific receptors or enzymes, potentially leading to more effective treatments for a range of diseases and conditions.
Used in Chemical Synthesis:
2-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is also used as a versatile building block in organic synthesis, particularly for the creation of complex molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science. Its reactivity and functional groups make it a valuable component in the synthesis of new compounds with diverse properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 174346-82-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,3,4 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 174346-82:
(8*1)+(7*7)+(6*4)+(5*3)+(4*4)+(3*6)+(2*8)+(1*2)=148
148 % 10 = 8
So 174346-82-8 is a valid CAS Registry Number.
174346-82-8Relevant articles and documents
QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITOR, COMPOSITIONS, METHODS OF MAKING THEM AND THEIR USE
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Page/Page column 521, (2020/05/13)
The present disclosure relates to new compounds or pharmaceutically acceptable salts or stereoisomers thereof of formula I as inhibitors of receptor tyrosine kinases (RTK), in particular extracellular mutants of ErbB-receptors. The present disclosure also relates to methods of preparation these compounds, compositions comprising these compounds, and methods of using them in the treatment of cancer in mammals (e.g. humans).
Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases
Evans, Gary B.,Furneaux, Richard H.,Greatrex, Ben,Murkin, Andrew S.,Schramm, Vern L.,Tyler, Peter C.
, p. 948 - 956 (2008/09/19)
N-Ribosyl phosphorylases and hydrolases catalyze nucleophilic displacement reactions by migration of the cationic ribooxacarbenium carbon from the fixed purine to phosphate and water nucleophiles, respectively. As the lysis reaction progresses along the r
Cathepsin cysteine protease inhibitors
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Page 19, (2010/02/06)
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of Cathepsins K and L. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
