174485-82-6 Usage
Description
5-Nitropyridine-2-sulfonyl chloride is an organic compound characterized by its unique chemical structure, which features a nitro group at the 5-position and a sulfonyl chloride group at the 2-position of the pyridine ring. 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE is known for its reactivity and versatility in various chemical reactions, making it a valuable intermediate in the synthesis of different pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
5-Nitropyridine-2-sulfonyl chloride is used as a key intermediate in the synthesis of hydroxypyrone derivatives, which possess HIV protease inhibitory properties. These derivatives are of significant interest in the development of new antiretroviral drugs, as they can potentially help in the treatment of HIV and AIDS by inhibiting the replication of the virus.
In the synthesis of hydroxypyrone derivatives, 5-nitropyridine-2-sulfonyl chloride serves as a crucial building block, allowing for the formation of the desired molecular structure with the necessary functional groups. The HIV protease inhibitory activity of these derivatives is attributed to their ability to bind to the active site of the HIV protease enzyme, thereby preventing the cleavage of viral polyproteins and ultimately suppressing the replication of the virus.
Furthermore, the reactivity of 5-nitropyridine-2-sulfonyl chloride can be exploited in other chemical reactions to synthesize a wide range of compounds with diverse applications in the pharmaceutical industry. Its utility as a versatile reagent makes it an important tool in the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 174485-82-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,4,8 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 174485-82:
(8*1)+(7*7)+(6*4)+(5*4)+(4*8)+(3*5)+(2*8)+(1*2)=166
166 % 10 = 6
So 174485-82-6 is a valid CAS Registry Number.
174485-82-6Relevant articles and documents
BORON-CONTAINING SMALL MOLECULES
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Page/Page column 137, (2012/06/05)
This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.
PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS
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, (2008/06/13)
The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1
