174799-96-3

Basic information

• Product Name: Glycine, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-N-(phenylmethyl)-, phenylmethyl ester
• CAS NO: 174799-96-3
• Molecular Formula: C25H34N2O4
• Molecular Weight: 426.556
• Mol File: 174799-96-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Glycine, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-N-(phenylmethyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-N-(phenylmethyl)-, phenylmethyl ester(174799-96-3)
• EPA Substance Registry System: Glycine, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-N-(phenylmethyl)-, phenylmethyl ester(174799-96-3)

Safety Data

• Hazardous Substances Data: 174799-96-3(Hazardous Substances Data)

Upstream product

• 90914-09-3 N⁽¹⁾-benzyl-N⁽⁴⁾-(tert-butyloxycarbonyl)-1,4-diaminobutane 
• 5437-45-6 Benzyl bromoacetate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 68076-36-8 1-amino-4-[(tert-butyloxycarbonyl)amino]butane 

Downstream Products

• 171856-09-0 N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-(5-((tert-butoxycarbonyl)amino)butyl)glycine 

Relevant articles and documents

Building Units for N-Backbone Cyclic Peptides. 3. Synthesis of Protected Nα-(ω-Aminoalkyl)amino Acids and Nα-(ω-Carboxyalkyl)amino Acids

An improved synthesis of a family of amino acids that contain ω-aminoalkyl groups and of a new family containing ω-carboxyalkyl groups linked to the α-amine is described. The synthesis was performed by alkylation of suitably monoprotected alkylenediamines and protected ω-amino acids with triflates of α-hydroxy acid esters. The reaction proceeded with inversion of configuration yielding optically pure products. The Nα-(ω-aminoalkyl)amino acids and Nα-(ω-carboxyalkyl)amino acids were orthogonally protected to allow their incorporation into peptides by solid-phase peptide synthesis (SPPS) methodology.