176244-21-6

Basic information

• Product Name: 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI)
• Synonyms: 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI);5,6-difluoro-2,3-dihydro-1H-1,3-benzodiazol-2-one
• CAS NO: 176244-21-6
• Molecular Formula: C₇H₄F₂N₂O
• Molecular Weight: 170.1162664
• Product Categories: BENZIMIDAZOLE
• Mol File: 176244-21-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI)(176244-21-6)
• EPA Substance Registry System: 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI)(176244-21-6)

Safety Data

• Hazardous Substances Data: 176244-21-6(Hazardous Substances Data)

Usage

General Description

2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI) is a chemical compound with the molecular formula C7H5F2N3O. It is a heterocyclic organic compound that contains a benzimidazole ring system with two fluorine atoms attached to the 5th and 6th positions. 2H-Benzimidazol-2-one,5,6-difluoro-1,3-dihydro-(9CI) may have potential applications in pharmaceutical and medicinal chemistry due to its unique chemical structure and properties. Further research and studies are needed to explore its potential uses and biological activity.

Upstream product

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Downstream Products

• 142356-63-6 2-Chloro-5,6-difulorobenzimidazole 

Relevant articles and documents

Engineering the solid state with 2-benzimidazolones

Six derivatives of 2-benzimidazolone, disubstituted in the 4 and 5 positions, have been synthesized, and their structures have been determined in the solid state. Four of these compounds crystallize as molecular tapes. Compounds 1-(CH3)2, 1-CI2, and 1-Br2 form tapes that pack with their long axes parallel; compounds 1-H2 and 2-H2 form tapes that pack with their long axes at an angle to one another. Compounds 1-F2 and 1-I2 crystallize with a three-dimensional network of hydrogen bonds. The packing arrangement of molecular tapes is rationalized on the basis of closest packing and electrostatic interactions between aromatic rings. The occurrence of the network motif rather than the tape motif for 1-F2 and 1-I2 is rationalized on the basis of secondary interactions involving the halogen atoms.

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Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell.