17691-02-0

Basic information

• Product Name: P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE
• Synonyms: P-AMINOPHENYL-B-D-LACTOSIDE;P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE;P-aminophenyl-B-D-lactopyranoside;4-Aminophenyl-beta-D-lactopyranoside;p-Aminophenyl-beta-D-lactoside;4-Aminophenyl 4-O-b-D-galactopyranosyl-b-D-glucopyranoside;4-Aminophenyl b-D-lactopyranoside;p-Aminophenyl b-lactoside
• CAS NO: 17691-02-0
• Molecular Formula: C₁₈H₂₇NO₁₁
• Molecular Weight: 433.41
• EINECS: 1533716-785-6
• Product Categories: Oligosaccharides;Amines;Aromatics
• Mol File: 17691-02-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 200-204°C
• Boiling Point: 774.6 °C at 760 mmHg
• Flash Point: 422.3 °C
• Appearance: off-white crystalline solid
• Density: 1.64g /cm³
• Vapor Pressure: 3E-25mmHg at 25°C
• Refractive Index: 1.675
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly, Heated), Water (Slightly)
• CAS DataBase Reference: P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE(17691-02-0)
• EPA Substance Registry System: P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE(17691-02-0)

Safety Data

• Hazardous Substances Data: 17691-02-0(Hazardous Substances Data)

Usage

Description

P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE, also known as p-Aminophenyl β-D-lactopyranoside, is a synthetic carbohydrate protein conjugate that exists as an off-white crystalline solid. It is a valuable compound in the field of immunology and biochemistry due to its unique properties and potential applications.

Uses

Used in Immunology:
P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE is used as an antigen or immunogen for [application reason] in the study and development of vaccines and immunotherapies. Its ability to stimulate an immune response makes it a promising candidate for the creation of vaccines against various diseases.
Used in Biochemical Research:
In the field of biochemistry, P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE is used as a substrate or inhibitor for [application reason] the study of enzymes, particularly glycosidases. Its unique structure allows researchers to investigate the mechanisms of these enzymes and develop potential therapeutic agents.
Used in Drug Development:
P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE is also used as a lead compound for [application reason] the development of new drugs targeting various diseases. Its interaction with specific enzymes and receptors can be exploited to design novel therapeutic agents with improved efficacy and selectivity.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE is used as a key intermediate for [application reason] the synthesis of complex carbohydrate-based drugs and drug delivery systems. Its versatility and reactivity make it an essential component in the development of innovative pharmaceutical products.
Used in Diagnostics:
P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE is employed as a diagnostic marker for [application reason] the detection and monitoring of certain diseases, particularly those involving abnormal glycosylation patterns. Its unique properties enable the development of highly sensitive and specific diagnostic tools.

InChI:InChI=1/C18H27NO11/c19-7-1-3-8(4-2-7)27-17-15(26)13(24)16(10(6-21)29-17)30-18-14(25)12(23)11(22)9(5-20)28-18/h1-4,9-18,20-26H,5-6,19H2/t9-,10-,11+,12+,13-,14-,15-,16-,17-,18+/m1/s1

Upstream product

• 4419-94-7 4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside 
• 135253-84-8 4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside 
• 2021-84-3 α-galactosyl fluoride 
• 20818-25-1 4-aminophenyl β-D-glucopyranoside 
• 5987-78-0 p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyde 
• 2492-87-7 4-nitrophenyl-β-D-glucoside 
• 100-02-7 4-nitro-phenol 
• 4753-07-5 2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide 
• 84034-75-3 4-nitrophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside 
• 196608-23-8 p-nitrophenyl β-D-galactopyranosyl-(1->4)-β-D-galactopyranoside 
• 5965-66-2 LACTOSE 
• 3616-19-1 1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose 

Downstream Products

• 135253-89-3 N-{4-[(2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-phenyl}-acrylamide 
• 94367-66-5 p-succinylamidophenyl β-lactoside 

Relevant articles and documents

Solid-phase oligosaccharide and glycopeptide synthesis using glycosynthases

Enzymatic approaches for the preparation of oligosaccharides are interesting alternatives to traditional chemical synthesis, the main advantage being the regio- and stereoselectivity offered without the need for protecting groups. The use of solid-phase techniques offers easy workup procedures and the prospect of automatability. Here, we report the first application of glycosynthases to solid-phase oligosaccharide synthesis by use of the 51 kDa serine and glycine mutants of Agrobacterium sp. β-glucosidase, Abg E358S and E358G. Acceptors were linked to PEGA resin through a backbone amide linker (BAL), and using these mutated enzymes, a galactose moiety was transferred from a donor sugar, α-D-galactosyl fluoride, with high efficiency (>90%) together with excellent recovery of material. Furthermore, it was demonstrated that a resin-bound model glycopeptide was also an acceptor for the glycosynthase.

Synthesis of polyanionic glycopolymers for the facile assembly of glycosyl arrays

Polyanionic glycopolymers were synthesized aiming at establishing a simple process for assembling glycosyl arrays. The synthetic glycopolymers carry the key carbohydrate epitopes of α-d-galactobioside (Gb2), β-lactoside, and α-d-mannopyranoside

Sugar-modified cytostatics

The invention relates to cytostatics which, by modification with sugar, are tumor-specific. Suitable spacers ensure serum stability and at the same time an intracellular action.