17722-14-4 Usage
Description
N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE, a chemical compound with the molecular formula C17H14Cl2N2O2, is a malonamide derivative featuring two amide groups attached to a malonate backbone. The presence of 3-chloro-phenyl groups endows it with unique properties, making it a versatile reagent in organic synthesis, especially for the production of pharmaceuticals and agrochemicals. Its utility as a chelating agent for metal ions and a catalyst in various chemical transformations highlights its importance in the chemical industry. However, due to its potential hazards, it is crucial to handle this compound with proper safety protocols.
Uses
Used in Organic Synthesis:
N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE is used as a reagent in organic synthesis for its ability to participate in a wide range of chemical reactions, facilitating the production of pharmaceuticals and agrochemicals. Its unique structural features contribute to its effectiveness in these applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE is used as a key intermediate in the synthesis of various drug molecules. Its role in organic synthesis makes it instrumental in creating complex pharmaceutical compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE is utilized as a reagent for the synthesis of agrochemicals, such as pesticides and herbicides, due to its ability to enhance the properties of these compounds.
Used as a Chelating Agent:
N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE is used as a chelating agent for metal ions, which is important in various chemical processes where metal ion sequestration is necessary to prevent unwanted side reactions or to improve the efficiency of certain reactions.
Used as a Catalyst:
Furthermore, it serves as a catalyst in a variety of chemical transformations, accelerating the rate of reactions without being consumed in the process, which is vital for improving the efficiency of chemical processes in both research and industrial settings.
Safety Considerations:
Due to the potential hazards associated with N,N''-BIS-(3-CHLORO-PHENYL)-MALONAMIDE, it is essential to handle this compound with care, following proper safety protocols to minimize risks to both individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 17722-14-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,7,2 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17722-14:
(7*1)+(6*7)+(5*7)+(4*2)+(3*2)+(2*1)+(1*4)=104
104 % 10 = 4
So 17722-14-4 is a valid CAS Registry Number.
17722-14-4Relevant articles and documents
HCV NS3 protease inhibitors
-
Page/Page column 86, (2016/06/01)
The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors
Sechi, Mario,Azzena, Ugo,Delussu, Maria Paola,Dallocchio, Roberto,Dessi, Alessandro,Cosseddu, Alessia,Pala, Nicolino,Neamati, Nouri
experimental part, p. 2442 - 2461 (2009/04/05)
HIV-1 integrase (IN) is an attractive and validated target for the development of novel therapeutics against AIDS. In the search for new IN inhibitors, we designed and synthesized three series of bis-amide and hydrazide-containing derivatives of malonic acid. We performed a docking study to investigate the potential interactions of the title compounds with essential amino acids on the IN active site.
Synthesis of Benzo-halogenated 4-Hydroxy-2(1H)-quinolones
Kappe, Thomas,Karem, Abdel S.,Stadlbauer, Wolfgang
, p. 857 - 862 (2007/10/02)
Malondianilides 3 derived from dichloro substituted anilines 2 undergo cyclization to afford 4-hydroxy-2(1H)-quinolones 4 in very good yields using methane sulfonic acid-phosphorus pentoxide as catalyst. 3,4-Dichloro anilines 5 can be shown to yield two i