17744-98-8 Usage
General Description
IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETONITRILE is a chemical compound belonging to the imidazo[1,2-a]pyridine class. It is also known by the chemical name 3-cyanomidazo[1,2-a]pyridine. IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETONITRILE is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various pharmaceutical drugs and active ingredients. It is a white to off-white solid, and its molecular structure consists of an imidazopyridine ring fused with a cyanomethyl group. IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETONITRILE has potential applications in the development of new drugs and also serves as an important intermediate in the production of various chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 17744-98-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,7,4 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17744-98:
(7*1)+(6*7)+(5*7)+(4*4)+(3*4)+(2*9)+(1*8)=138
138 % 10 = 8
So 17744-98-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7N3/c10-5-4-8-7-11-9-3-1-2-6-12(8)9/h1-3,6-7H,4H2
17744-98-8Relevant articles and documents
INDOLE AHR INHIBITORS AND USES THEREOF
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Paragraph 00283, (2018/11/22)
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
Preparation method of minodronic acid
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Paragraph 0027-0028; 0035-0036; 0043-0044; 0051-0052, (2017/09/02)
The invention discloses a preparation method of minodronic acid. The method uses 1-[imidazo(1,2-alpha)pyridine-3-ly]methyl-N,N,N-trimethyliodide and sodium cyanide as raw materials, and comprises the steps of a cyan substitution reaction, a hydrolysis reaction, a phosphorylation reaction and refining. According to the preparation method of minodronic acid provided by the invention, a usage amount of the sodium cyanide is strictly controlled; DMF is used as a solvent, solubility of the raw materials is good, a system is in a homogeneous phase; silicagel columns are used, so that purities with deep colors and large polarities and the ionic compound sodium cyanide can be intercepted, and a nitrile compound, a first midbody, with high purity is acquire, and a basis is established for smoothness of the whole technology.