177897-10-8

Basic information

• Product Name: 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid methyl ester
• Synonyms: 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid methyl ester
• CAS NO: 177897-10-8
• Molecular Weight: 523.627
• Mol File: 177897-10-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid methyl ester(177897-10-8)
• EPA Substance Registry System: 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid methyl ester(177897-10-8)

Safety Data

• Hazardous Substances Data: 177897-10-8(Hazardous Substances Data)

Upstream product

• 6908-41-4 4-(methoxycarbonyl)benzyl alcohol 
• 3006-96-0 3-hydroxymethyl-benzoic acid 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 56-18-8 bis(3-aminopropyl)amine 
• 82409-02-7 bis[3-(t-butoxycarbonylamino)propyl]amine 
• 105095-22-5 methyl 4-[(4-nitrophenoxy)carbonyloxymethyl]benzoate 

Downstream Products

• 201211-58-7 4-{[Bis-(3-tert-butoxycarbonylamino-propyl)-carbamoyloxy]-methyl}-benzoic acid 

Relevant articles and documents

Solid phase synthesis of polyamine conjugates for the study of trypanothione reductase

A number of polyamine scaffolds were synthesised, enabling the facile preparation of a variety of polyamine conjugates using both Boc and Fmoc protecting group strategies. Products were released from the solid support by treatment with either triflic acid/trifluoroacetic acid or trifluoroacetic acid. The trypanosomal metabolite N1, N6-bis(glurathionyl)spermidine [trypanothione], and a range of related analogues were prepared for biological evaluation as previously communicated.