177949-92-7 Usage
Description
(E)-4,4,5,5-tetramethyl-2-(3-methylbut-1-en-1-yl)-1,3,2-dioxaborolane, also known as TMEDA, is a chemical compound that serves as a ligand in organic synthesis and catalysis. It is a colorless liquid with a molecular formula of C11H21BO2 and a molecular weight of 200.1 g/mol. TMEDA is a versatile chelating agent, forming stable complexes with a wide range of metal ions, particularly transition metals. Its chelating ability and steric bulk make it useful in coordinating metal atoms in catalytic processes, such as polymerization and cross-coupling reactions. TMEDA is also utilized in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and fine chemicals.
Uses
Used in Pharmaceutical Industry:
TMEDA is used as a ligand in the synthesis of pharmaceuticals for its ability to form stable complexes with metal ions, which aids in the coordination of metal atoms in catalytic processes. This enhances the efficiency and selectivity of the reactions, leading to the production of desired pharmaceutical compounds.
Used in Agrochemical Industry:
In the agrochemical industry, TMEDA is employed as a ligand for the synthesis of various agrochemicals. Its chelating properties and steric bulk enable the formation of stable complexes with metal ions, facilitating the catalytic processes required for the production of agrochemical compounds.
Used in Fine Chemicals Industry:
TMEDA is utilized as a ligand in the synthesis of fine chemicals, where its ability to chelate with metal ions and provide steric bulk is crucial for the coordination of metal atoms in catalytic processes. This contributes to the efficient production of fine chemicals with specific properties and applications.
Used in Polymerization:
TMEDA is used as a ligand in polymerization reactions, where its chelating ability and steric bulk help coordinate metal atoms, leading to the formation of polymers with desired properties.
Used in Cross-Coupling Reactions:
TMEDA is employed as a ligand in cross-coupling reactions, a type of chemical reaction used to form carbon-carbon bonds. Its chelating properties and steric bulk facilitate the coordination of metal atoms, enhancing the efficiency and selectivity of the reaction.
Check Digit Verification of cas no
The CAS Registry Mumber 177949-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,9,4 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 177949-92:
(8*1)+(7*7)+(6*7)+(5*9)+(4*4)+(3*9)+(2*9)+(1*2)=207
207 % 10 = 7
So 177949-92-7 is a valid CAS Registry Number.
177949-92-7Relevant articles and documents
A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic Alcohols
Liu, Yangbin,Mazet, Clément
, p. 5638 - 5650 (2020/05/19)
A catalytic sequence for the diastereo- and enantioselective preparation of homoallylic alcohols with an adjacent quaternary (stereo)center is reported. The one-pot process relies on the use of a single (achiral or chiral) iridium complex to catalyze the concomitant isomerization of primary allylic alcohols and homoallylboronates into (chiral) aldehydes and allylboronates, respectively. In the same flask, a chiral Br?nsted acid is added next to engage the isomerization products into a stereocontrolled allylboration reaction. Structural variations have been performed on both the allylic alcohols and the homoallylboronates. This mild process affords an array of stereochemically congested and complex chiral secondary homoallylic alcohols in high yield, excellent diastereoselectivity, and usually high enantioselectivity.
