178032-64-9

Basic information

• Product Name: (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 178032-64-9
• Molecular Weight: 269.343
• Mol File: 178032-64-9.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline(178032-64-9)
• EPA Substance Registry System: (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline(178032-64-9)

Safety Data

• Hazardous Substances Data: 178032-64-9(Hazardous Substances Data)

Upstream product

• 4029-09-8 6,7-dimethoxy-1-phenyl-isoquinoline 
• 10172-51-7 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline 
• 20922-03-6 1-(propan-2-yl)isoquinoline 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 98-88-4 benzoyl chloride 
• 4118-36-9 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 1643770-97-1 (S)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-methoxy-2-phenylacetate 
• 922359-27-1 1-(6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)pent-4-en-1-one 
• 1346681-71-7 (1E)-4-hydroxy-1-mesityl-4-methylpent-1-en-3-one 
• 1017594-90-9 (1R)-1-phenyl-N-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 100-52-7 benzaldehyde 

Downstream Products

• 853650-68-7 (-)-6,7-dimethoxy-2-(oct-7-ynyl)-1R-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 4118-36-9 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 853650-66-5 (-)-2-(hept-6-ynyl)-6,7-dimethoxy-1R-phenyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

A through halogen bond activation isoquinoline asymmetric hydrogenation method

A through halogen bond activation isoquinoline asymmetric hydrogenation method, the catalyzing system is [...] complex, the activator is a halide. The reaction can be carried out under the following conditions, temperature: 25 - 100 °C; solvent: tetrahydr

A method catalyzed by iridium and used for bidirectional enantioselective synthesis of chiral tetrahydroisoquinoline

A method catalyzed by iridium and used for bidirectional enantioselective synthesis of chiral tetrahydroisoquinoline is provided. A catalysis system adopted by the method is a chiral diphosphine complex of iridium. By utilizing a single chiral source and

Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator

By employing halogenide trichloroisocyanuric acid as a traceless activation reagent, a general iridium-catalyzed asymmetric hydrogenation of isoquinolines and pyridines is developed with up to 99% ee. This method avoids tedious steps of installation and removal of the activating groups. The mechanism studies indicated that hydrogen halide generated in situ acted as an activator of isoquinolines and pyridines.