178315-47-4

Basic information

• Product Name: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-(1-phenylethyl)-3-(2-phenylethyl)-
• CAS NO: 178315-47-4
• Molecular Formula: C24H23NO2
• Molecular Weight: 357.452
• Mol File: 178315-47-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-(1-phenylethyl)-3-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-(1-phenylethyl)-3-(2-phenylethyl)-(178315-47-4)
• EPA Substance Registry System: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-(1-phenylethyl)-3-(2-phenylethyl)-(178315-47-4)

Safety Data

• Hazardous Substances Data: 178315-47-4(Hazardous Substances Data)

Upstream product

• 618-36-0 rac-methylbenzylamine 
• 85-44-9 phthalic anhydride 
• 3976-26-9 2-(1-phenylethyl)isoindoline-1,3-dione 
• 103-63-9 1-phenyl-2-bromoethane 

Relevant articles and documents

Formation of spiro indane derivatives from hydroxy lactams derived from N-(1-phenylethyl)-phthalimide and -pyridine-2,3-dicarboximide

Spiro[indane-1,7′-pyrrolo[3,4-b]pyridin]-5′-ones 18-22 are formed by acid-catalysed rearrangement from 7-aryl-7-hydroxy-6-(1-phenylethyl)-6,7-dihydropyrrolo[3,4-b]pyridin-5-ones. Further spiro indanes 39, 43 and 44 and spiro naphthalenes 41, 42, 45 and 46 are obtained from 3-(ω-phenylalkyl)-3-hydroxy-2-(1-phenylethyl)isoindolin-1-ones or from 7-(ω-phenylalkyl)-7-hydroxy-6-(1-phenylethyl)-6,7-dihydropyrrolo[3,4-b] pyridin-5-ones via α,α-cyclisation of N-acyliminium ion intermediates.