178896-79-2

Basic information

• Product Name: 6-(trifluoromethyl)-5-methoxyindoline
• Synonyms: 6-(trifluoromethyl)-5-methoxyindoline;5-Methoxy-6-(trifluoroMethyl)indoline;2,3-Dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole
• CAS NO: 178896-79-2
• Molecular Formula: C₁₀H₁₀F₃NO
• Molecular Weight: 217.189
• Mol File: 178896-79-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 83～84℃
• Boiling Point: 287℃
• Flash Point: 127℃
• Appearance: /
• Density: 1.262
• Vapor Pressure: 0.00263mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-(trifluoromethyl)-5-methoxyindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(trifluoromethyl)-5-methoxyindoline(178896-79-2)
• EPA Substance Registry System: 6-(trifluoromethyl)-5-methoxyindoline(178896-79-2)

Safety Data

• Hazardous Substances Data: 178896-79-2(Hazardous Substances Data)

Usage

General Description

6-(trifluoromethyl)-5-methoxyindoline is a chemical compound with the molecular formula C10H9F3NO. It is a derivative of indoline, which is a bicyclic aromatic heterocycle. The compound contains a trifluoromethyl group and a methoxy group, which are both attached to the nitrogen atom in the indoline ring. 6-(trifluoromethyl)-5-methoxyindoline is commonly used as a building block in organic synthesis and medicinal chemistry. It has potential applications in the development of pharmaceuticals and agrochemicals due to its unique structural features and properties. Additionally, its substituted indoline structure makes it an important intermediate in the synthesis of various biologically active compounds.

InChI:InChI=1/C10H10F3NO/c1-15-9-4-6-2-3-14-8(6)5-7(9)10(11,12)13/h4-5,14H,2-3H2,1H3

Upstream product

• 178896-78-1 5-methoxy-6-(trifluoromethyl)-1H-indole 
• 654-76-2 1-methoxy-4-nitro-2-(trifluoromethyl)benzene 
• 777-37-7 4-chloro-3-(trifluoromethyl)nitrobenzene 
• 178896-77-0 2-(5-methoxy-2-nitro-4-(trifluoromethyl)-phenyl)acetonitrile 

Downstream Products

• 181629-93-6 SB 228357 

Relevant articles and documents

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention relates to substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention concerns substituted indoline compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent