178910-14-0Relevant articles and documents
Synthesis of (Z)-nitroalkene derivatives through oxidative dehydrogenation coupling of α-aminocarbonyl compounds with nitromethane by copper catalysis
Zhu, Menghua,Chen, De,Zeng, Sheng,Xing, Chenhu,Deng, Wei,Xiang, Jiannan,Wang, Rui-Jia
supporting information, p. 3214 - 3219 (2018/07/21)
A novel copper-catalyzed cross-dehydrogenative coupling reaction of α-amino carbonyl compounds with nitromethane to synthesis of (Z)-nitroalkene derivatives has been established. (Z)-Nitroalkene derivatives are achieved through the cleavage of sp3 CsbndH bonds and formation of CsbndC double bond, with mild reaction conditions and excellent stereoselectivity.
Substituted 5,7-Diphenyl-pyrrolo[2,3d]pyrimidines: Potent inhibitors of the tyrosine kinase c-Src
Missbach, Martin,Altmann, Eva,Widler, Leo,Susa, Mira,Buchdunger, Elisabeth,Mett, Helmut,Meyer, Thomas,Green, Jonathan
, p. 945 - 949 (2007/10/03)
5,7-Diphenyl-pyrrolo[2,3d]pyrimidines represent a new class of highly potent inhibitors of the tyrosine kinase c-Src (IC50 50 nM) with specificity against a panel of different tyrosine kinases. The substitution pattern on the two phenyl rings