179408-54-9Relevant articles and documents
HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS
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, (2011/12/14)
The present invention generally relates to compounds that inhibit haematopoietic-prostaglandin D2 synthase (H-PGDS), to compositions containing them and to their use in treating or preventing conditions and diseases associated with H-PGDS, such
Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework
Ohnmacht, Stephan A.,Brenstrum, Tim,Bleicher, Konrad H.,McNulty, James,Capretta, Alfredo
, p. 5661 - 5663 (2007/10/03)
The use of a catalyst system based on Pd2dba3· CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha- adamantane allows for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.
MUSCARINIC AGONISTS
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Page 21, (2010/02/09)
The present invention relates to compounds of Formula (I): which are agonists of the M-1 muscarinic receptor.