17965-74-1

Basic information

• Product Name: 8-BROMO-1,6-NAPHTHYRIDINE
• Synonyms: 8-BROMO-1,6-NAPHTHYRIDINE;1,6-Naphthyridine, 8-bromo-
• CAS NO: 17965-74-1
• Molecular Formula: C8H5BrN2
• Molecular Weight: 209.04
• Mol File: 17965-74-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 312 °C at 760 mmHg
• Flash Point: 142.5 °C
• Appearance: /
• Density: 1.656 g/cm³
• Vapor Pressure: 0.000996mmHg at 25°C
• Refractive Index: 1.685
• PKA: 1.45±0.30(Predicted)
• CAS DataBase Reference: 8-BROMO-1,6-NAPHTHYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BROMO-1,6-NAPHTHYRIDINE(17965-74-1)
• EPA Substance Registry System: 8-BROMO-1,6-NAPHTHYRIDINE(17965-74-1)

Safety Data

• Hazardous Substances Data: 17965-74-1(Hazardous Substances Data)

Usage

General Description

8-Bromo-1,6-naphthyridine is a chemical compound with the molecular formula C9H6BrN. It is a heterocyclic compound that contains a bromine atom and a naphthyridine ring structure. 8-Bromo-1,6-naphthyridine is known for its use in the synthesis of pharmaceuticals and agrochemicals, as well as in various organic reactions as a reagent. It is a white to light yellow solid that is sparingly soluble in water but soluble in organic solvents such as acetone and dichloromethane. It is important to handle and store 8-bromo-1,6-naphthyridine with caution due to its potential health and environmental hazards, and safety precautions should be followed when working with this chemical.

InChI:InChI=1/C8H5BrN2/c9-7-5-10-4-6-2-1-3-11-8(6)7/h1-5H

Upstream product

• 253-72-5 1,6-naphthyridine 
• 504-24-5 4-aminopyridine 

Downstream Products

• 6052-72-8 5,6,9,10-tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine 

Relevant articles and documents

HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the CXCR4 pathway.

ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION

Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise (I) wherein: Ra, R1, R2 and R3 are each, independently, hydrogen, or a substituent selected from halogen, CF3, alkyl, alkoxy, MeSO2, amino or aminocarbonyl (each optionally substituted by one or two groups selected from alkyl and benzyl) carboxy, or alkoxycarbonyl; or two adjacent of Ra and R1-4 together can form a 5-7 membered carbocyclic or heterocyclic ring which is optionally substituted by a substituent defined above; R4 is hydrogen, halogen, or alkyl; R5 is hydrogen, alkyl, arylalkyl, or aryl; R6 is hydrogen, halogen, CF3, CN, carbamide, alkoxy or benzyloxy; X1, X2 and X3 are each carbon or one of X1, X2 or X3 may be nitrogen; Y is CH or nitrogen; and Z is carbon or nitrogen; or pharmaceutically acceptable salts thereof.